Epigenetics in renal cell cancer: mechanisms and clinical applications
SC Joosten, KM Smits, MJ Aarts, V Melotte… - Nature Reviews …, 2018 - nature.com
Renal cell carcinoma (RCC) is characterized by an infrequent number of somatic mutations.
By contrast, epigenetic aberrations are commonly found in RCC, indicating that epigenetic …
By contrast, epigenetic aberrations are commonly found in RCC, indicating that epigenetic …
[HTML][HTML] The fundamental role of miR-10b in metastatic cancer
P Sheedy, Z Medarova - American journal of cancer research, 2018 - ncbi.nlm.nih.gov
Small, non-coding strands of RNA have been identified as a significant player in the
pathology of cancer. One of the first miRNAs to be shown as having aberrant expression in …
pathology of cancer. One of the first miRNAs to be shown as having aberrant expression in …
miR‐372 suppresses tumour proliferation and invasion by targeting IGF 2 BP 1 in renal cell carcinoma
X Huang, M Huang, L Kong, Y Li - Cell proliferation, 2015 - Wiley Online Library
Objectives Micro RNA s (mi RNA s) are endogenous small non‐coding RNA s that regulate
proteins and mRNA s for degradation or translational suppression. Up to now, the role of …
proteins and mRNA s for degradation or translational suppression. Up to now, the role of …
The level of circulating miRNA-10b and miRNA-373 in detecting lymph node metastasis of breast cancer: potential biomarkers
W Chen, F Cai, B Zhang, Z Barekati, XY Zhong - Tumor Biology, 2013 - Springer
MicroRNAs (miRNAs) are a class of small noncoding RNAs whose expression changes are
associated with cancer development and invasion. We hypothesized that miR-10b and miR …
associated with cancer development and invasion. We hypothesized that miR-10b and miR …
[HTML][HTML] Pattern recognition for predictive, preventive, and personalized medicine in cancer
T Cheng, X Zhan - EPMA Journal, 2017 - Springer
Predictive, preventive, and personalized medicine (PPPM) is the hot spot and future
direction in the field of cancer. Cancer is a complex, whole-body disease that involved multi …
direction in the field of cancer. Cancer is a complex, whole-body disease that involved multi …
[HTML][HTML] MiR-130b is a prognostic marker and inhibits cell proliferation and invasion in pancreatic cancer through targeting STAT3
G Zhao, J Zhang, Y Shi, Q Qin, Y Liu, B Wang, K Tian… - PloS one, 2013 - journals.plos.org
Accumulating evidence indicates that microRNAs (miRNAs) are aberrantly expressed in
human cancer and contribute to the tumorigenesis, but their roles in pancreatic cancer are …
human cancer and contribute to the tumorigenesis, but their roles in pancreatic cancer are …
MicroRNA-130b promotes tumor development and is associated with poor prognosis in colorectal cancer
T Colangelo, A Fucci, C Votino, L Sabatino… - Neoplasia, 2013 - Elsevier
Abstract MicroRNA-130b (miR-130b) is involved in several biologic processes; its role in
colorectal tumorigenesis has not been addressed so far. Herein, we demonstrate that miR …
colorectal tumorigenesis has not been addressed so far. Herein, we demonstrate that miR …
[HTML][HTML] Integrated microRNA and mRNA signature associated with the transition from the locally confined to the metastasized clear cell renal cell carcinoma …
Z Wotschofsky, L Gummlich, J Liep, C Stephan, E Kilic… - PloS one, 2016 - journals.plos.org
Background MicroRNAs (miRNAs) regulate gene expression by interfering translation or
stability of target transcripts. This interplay between miRNA and their mRNA has been …
stability of target transcripts. This interplay between miRNA and their mRNA has been …
[HTML][HTML] Hsa-miR-139-5p inhibits proliferation and causes apoptosis associated with down-regulation of c-Met
Abstract Hsa-miRNA-139-5p (miR-139-5p) has recently been discovered having anticancer
efficacy in different organs. However, the role of miR-139-5p on lung cancer is still …
efficacy in different organs. However, the role of miR-139-5p on lung cancer is still …
The regulation and function of microRNAs in kidney diseases
MicroRNAs (miRNA) are endogenous short noncoding RNAs, which regulate virtually all
major cellular processes by inhibiting target gene expression. In kidneys, miRNAs have …
major cellular processes by inhibiting target gene expression. In kidneys, miRNAs have …