Role of dietary fructose and hepatic de novo lipogenesis in fatty liver disease

S Softic, DE Cohen, CR Kahn - Digestive diseases and sciences, 2016 - Springer
Nonalcoholic fatty liver disease (NAFLD) is a liver manifestation of metabolic syndrome.
Overconsumption of high-fat diet (HFD) and increased intake of sugar-sweetened …

[HTML][HTML] Omega-3 supplementation and non-alcoholic fatty liver disease: a systematic review and meta-analysis

HM Parker, NA Johnson, CA Burdon, JS Cohn… - Journal of …, 2012 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a frequent accompaniment of obesity and
insulin resistance. With the prevalence approaching 85% in obese populations, new …

[HTML][HTML] An integrated understanding of the rapid metabolic benefits of a carbohydrate-restricted diet on hepatic steatosis in humans

A Mardinoglu, H Wu, E Bjornson, C Zhang… - Cell metabolism, 2018 - cell.com
A carbohydrate-restricted diet is a widely recommended intervention for non-alcoholic fatty
liver disease (NAFLD), but a systematic perspective on the multiple benefits of this diet is …

[PDF][PDF] Nonalcoholic fatty liver disease: from steatosis to cirrhosis

GC Farrell, CZ Larter - Hepatology, 2006 - Wiley Online Library
Nonalcoholic steatohepatitis (NASH), the lynchpin between steatosis and cirrhosis in the
spectrum of nonalcoholic fatty liver disorders (NAFLD), was barely recognized in 1981 …

The epidemiology of nonalcoholic fatty liver disease: a global perspective

M Lazo, JM Clark - Seminars in liver disease, 2008 - thieme-connect.com
Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized cause of liver
disease in the United States and worldwide. With obesity being an important risk factor …

Microbial translocation across the GI tract

JM Brenchley, DC Douek - Annual review of immunology, 2012 - annualreviews.org
The lumen of the gastrointestinal (GI) tract is home to an enormous quantity of different
bacterial species, our microbiota, that thrive in an often symbiotic relationship with the host …

[PDF][PDF] Toll‐like receptor 4 is involved in the development of fructose‐induced hepatic steatosis in mice

A Spruss, G Kanuri, S Wagnerberger, S Haub… - …, 2009 - Wiley Online Library
A link between dietary fructose intake, gut‐derived endotoxemia, and nonalcoholic fatty liver
disease (NAFLD) has been suggested by the results of human and animal studies. To …

Spectrum of liver disease in type 2 diabetes and management of patients with diabetes and liver disease

KG Tolman, V Fonseca, A Dalpiaz, MH Tan - Diabetes care, 2007 - Am Diabetes Assoc
METHODS—A Medline search without limitations of date (as of October 2005), language, or
humans was carried out by the authors. The following medical subject headings were …

Clinical impact of sexual dimorphism in non‐alcoholic fatty liver disease (NAFLD) and non‐alcoholic steatohepatitis (NASH)

P Burra, D Bizzaro, A Gonta, S Shalaby… - Liver …, 2021 - Wiley Online Library
NAFLD/NASH is a sex‐dimorphic disease, with a general higher prevalence in men. Women
are at reduced risk of NAFLD compared to men in fertile age, whereas after menopause …

Causes and metabolic consequences of fatty liver

N Stefan, K Kantartzis, HU Häring - Endocrine reviews, 2008 - academic.oup.com
Type 2 diabetes and cardiovascular disease represent a serious threat to the health of the
population worldwide. Although overall adiposity and particularly visceral adiposity are …