Simple Summary Due to the lack of selectivity and the severe side-effects, cytostatics are the
drugs of the present but not of the future and consequently new anticancer strategies must …

Heat shock proteins (HSPs) are a large molecular chaperone family classified by their
molecular weights, including HSP27, HSP40, HSP60, HSP70, HSP90, and HSP110. HSPs …

Aims Prostate cancer continues to be one of the main global health issues in men.
Neuropeptide substance P (SP) acting via neurokinin-1receptor (NK1R) promotes …

In folk medicine, Aloe, a genus of Aloaceae, is constantly developed into laxative drugs or
products and skin remedies with tremendous popularity worldwide. However, almost all …

The tumor microenvironment (TME) and its components have recently attracted tremendous
attention in cancer treatment strategies, as alongside the genetic and epigenetic alterations …

Background Cervical cancer, an aggressive gynecological cancer, seriously threatens
women's health worldwide. It is recently reported that neuropeptide substance P (SP) …

Glioblastoma multiforme (GBM) is the most malignant type of cerebral neoplasm in adults
with a poor prognosis. Currently, combination therapy with different anti‐cancer agents is at …

Introduction. Glioblastoma is the most malignant brain tumor with different therapeutic
protocols, including surgery, radiotherapy, and chemotherapy. Substance P (SP), a peptide …

Abstract Background Substance P (SP) has a crucial role in cancer initiation and
progression via binding to its specific receptor (NK1R). Various evidence confirmed the …

Background. Osteosarcoma, the most frequent osteogenic malignancy, has become a
serious public health challenge due to its high morbidity rates and metastatic potential …