Current clinical tools for breast cancer (BC) diagnosis are insufficient but liquid biopsy of
different bodily fluids has recently emerged as a minimally invasive strategy that provides a …

Cell surface glycosylation has a variety of functions, and its dysregulation in cancer
contributes to impaired signaling, metastasis and the evasion of the immune responses …

The glycoproteome remains severely understudied because of significant analytical
challenges associated with glycoproteomics, the system-wide analysis of intact …

Colorectal cancer (CRC) is one of the costliest health problems and ranks second in cancer-
related mortality in developed countries. With the aid of proteomics, many protein …

The ST6GAL1 sialyltransferase, which adds α2–6 linked sialic acids to N-glycosylated
proteins, is overexpressed in a wide range of human malignancies. Recent studies have …

N-glycan, a fundamental and versatile protein modification in mammals, plays critical roles
in various physiological and pathological events including cancer progression. The …

Despite the evidences of elevated expression of Mer tyrosine kinase (MerTK) in multiple
human cancers, mechanisms underlying the oncogenic roles of MerTK in hepatocellular …

Glycans within human lungs are recognized by many pathogens such as influenza A virus
(IAV), yet little is known about their structures. Here we present the first analysis of the N-and …

While aberrant protein glycosylation is a recognized characteristic of human cancers,
advances in glycoanalytics continue to discover new associations between glycoproteins …

Facilitated by advances in the separation sciences, mass spectrometry and informatics,
glycoproteomics, the analysis of intact glycopeptides at scale, has recently matured enabling …