Critical assessment of methods for predicting the 3D structure of proteins and protein complexes
SJ Wodak, S Vajda, MF Lensink… - Annual review of …, 2023 - annualreviews.org
Advances in a scientific discipline are often measured by small, incremental steps. In this
review, we report on two intertwined disciplines in the protein structure prediction field …
review, we report on two intertwined disciplines in the protein structure prediction field …
Investigating protein–peptide interactions using the Schrödinger computational suite
J Bhachoo, T Beuming - Modeling peptide-protein interactions: methods …, 2017 - Springer
The Schrödinger software suite contains a broad array of computational chemistry and
molecular modeling tools that can be used to study the interaction of peptides with proteins …
molecular modeling tools that can be used to study the interaction of peptides with proteins …
The ClusPro web server for protein–protein docking
Abstract The ClusPro server (https://cluspro. org) is a widely used tool for protein–protein
docking. The server provides a simple home page for basic use, requiring only two files in …
docking. The server provides a simple home page for basic use, requiring only two files in …
Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy
G Luxán, JC Casanova, B Martínez-Poveda… - Nature medicine, 2013 - nature.com
Left ventricular noncompaction (LVNC) causes prominent ventricular trabeculations and
reduces cardiac systolic function. The clinical presentation of LVNC ranges from …
reduces cardiac systolic function. The clinical presentation of LVNC ranges from …
A novel multi-epitope peptide vaccine against cancer: an in silico approach
Cancer immunotherapy has an outstanding position in cancer prevention and treatment. In
this kind of therapy, the immune system is activated to eliminate cancerous cells. Multi …
this kind of therapy, the immune system is activated to eliminate cancerous cells. Multi …
The role of distant mutations and allosteric regulation on LovD active site dynamics
Natural enzymes have evolved to perform their cellular functions under complex selective
pressures, which often require their catalytic activities to be regulated by other proteins. We …
pressures, which often require their catalytic activities to be regulated by other proteins. We …
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells
S Pei, M Minhajuddin, KP Callahan, M Balys… - Journal of Biological …, 2013 - ASBMB
The development of strategies to eradicate primary human acute myelogenous leukemia
(AML) cells is a major challenge to the leukemia research field. In particular, primitive …
(AML) cells is a major challenge to the leukemia research field. In particular, primitive …
Designing an efficient multi-epitope peptide vaccine against Vibrio cholerae via combined immunoinformatics and protein interaction based approaches
Cholera continues to be a major global health concern. Among different Vibrio cholerae
strains, only O1 and O139 cause acute diarrheal diseases that are related to epidemic and …
strains, only O1 and O139 cause acute diarrheal diseases that are related to epidemic and …
Application of asymmetric statistical potentials to antibody–protein docking
Motivation: An effective docking algorithm for antibody–protein antigen complex prediction is
an important first step toward design of biologics and vaccines. We have recently developed …
an important first step toward design of biologics and vaccines. We have recently developed …
Vaccinomics approach for developing multi-epitope peptide pneumococcal vaccine
H Dorosti, M Eslami, M Negahdaripour… - Journal of …, 2019 - Taylor & Francis
Streptococcus pneumoniae is a leading cause of some diseases such as pneumonia,
sepsis, and meningitis mostly in children less than 5 years of age. Presently, two types of …
sepsis, and meningitis mostly in children less than 5 years of age. Presently, two types of …