[HTML][HTML] Antidiabetic potential of medicinal plants and their active components

B Salehi, A Ata, N V. Anil Kumar, F Sharopov… - Biomolecules, 2019 - mdpi.com
Diabetes mellitus is one of the major health problems in the world, the incidence and
associated mortality are increasing. Inadequate regulation of the blood sugar imposes …

The Genus Phyllanthus: An Ethnopharmacological, Phytochemical, and Pharmacological Review

X Mao, LF Wu, HL Guo, WJ Chen… - Evidence‐based …, 2016 - Wiley Online Library
The plants of the genus Phyllanthus (Euphorbiaceae) have been used as traditional
medicinal materials for a long time in China, India, Brazil, and the Southeast Asian countries …

[HTML][HTML] Identification and characterization of phenolics and terpenoids from ethanolic extracts of Phyllanthus species by HPLC-ESI-QTOF-MS/MS

S Kumar, A Singh, B Kumar - Journal of pharmaceutical analysis, 2017 - Elsevier
Phyllanthus species plants are a rich source of phenolics and widely used due to their
medicinal properties. A liquid chromatography–tandem mass spectrometry (LC–MS/MS) …

Novel antioxidant quinoxaline derivative: Synthesis, crystal structure, theoretical studies, antidiabetic activity and molecular docking study

M Missioui, S Mortada, W Guerrab, G Serdaroğlu… - Journal of Molecular …, 2021 - Elsevier
Abstract New quinoxaline derivative, N-(4-methyl-2-nitrophenyl)-2-(3-methyl-2-
oxoquinoxalin-1 (2H)-yl) acetamide (NPOQA) has been synthesized and characterized by …

[HTML][HTML] Phenolics Profiling of Carpobrotus edulis (L.) NEBr. and Insights into Molecular Dynamics of Their Significance in Type 2 Diabetes Therapy and Its …

S Sabiu, FO Balogun, SO Amoo - Molecules, 2021 - mdpi.com
Adverse effects associated with synthetic drugs in diabetes therapy has prompted the search
for novel natural lead compounds with little or no side effects. Effects of phenolic compounds …

[HTML][HTML] Phenolic content, acute toxicity of Ajuga iva extracts and assessment of their antioxidant and carbohydrate digestive enzyme inhibitory effects

S Fettach, HN Mrabti, K Sayah, A Bouyahya… - South African Journal of …, 2019 - Elsevier
The management of blood glucose level is the hallmark in the treatment of type 2 diabetes,
and this may be achieved through the inhibition of the digestive enzymes involved in …

[HTML][HTML] Gedunin and Azadiradione: Human Pancreatic Alpha-Amylase Inhibiting Limonoids from Neem (Azadirachta indica) as Anti-Diabetic Agents

S Ponnusamy, S Haldar, F Mulani, S Zinjarde… - PloS one, 2015 - journals.plos.org
Human pancreatic α-amylase (HPA) inhibitors offer an effective strategy to lower
postprandial hyperglycemia via control of starch breakdown. Limonoids from Azadirachta …

Antioxidant Activity and Inhibitory Potential of Cistus salviifolius (L.) and Cistus monspeliensis (L.) Aerial Parts Extracts against Key Enzymes Linked to …

K Sayah, I Marmouzi, H Naceiri Mrabti… - BioMed Research …, 2017 - Wiley Online Library
Cistus genus (Cistaceae) comprises several medicinal plants used in traditional medicines
to treat several pathological conditions including hyperglycemia. These include Cistus …

[HTML][HTML] Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis

G Brusotti, R Montanari, D Capelli, G Cattaneo… - Scientific reports, 2017 - nature.com
PPAR antagonists are ligands that bind their receptor with high affinity without
transactivation activity. Recently, they have been demonstrated to maintain insulin …

[HTML][HTML] Inhibitory effect of metformin and pyridoxamine in the formation of early, intermediate and advanced glycation end-products

S Ahmad, U Shahab, MH Baig, MS Khan, MS Khan… - PloS one, 2013 - journals.plos.org
Background Non-enzymatic glycation is the addition of free carbonyl group of reducing
sugar to the free amino groups of proteins, resulting in the formation of a Schiff base and an …