Rational design of chymotrypsin inhibitor 2 by optimizing non-native interactions

F B. da Silva, V M. de Oliveira… - Journal of chemical …, 2019 - ACS Publications
Rational design of proteins via mutagenesis is crucial for several biotechnological
applications. A significant challenge of the computational strategies used to predict …

The role of electrostatics and folding kinetics on the thermostability of homologous cold shock proteins

PHB Ferreira, FC Freitas, ME McCully… - Journal of chemical …, 2020 - ACS Publications
Understanding which aspects contribute to the thermostability of proteins is a challenge that
has persisted for decades, and it is of great relevance for protein engineering. Several types …

A influência da eletrostática na estabilidade de proteínas cold shock homólogas

PHB Ferreira - 2020 - bdtd.uftm.edu.br
Nas últimas décadas, as proteínas têm sido alvo de grande interesse industrial. As funções
que tais moléculas desempenham têm demonstrado utilidade nas mais variadas áreas …