Developmental regulation of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole‐propionic acid receptor subunit expression in forebrain and relationship to regional …

DM Talos, RE Fishman, H Park… - Journal of …, 2006 - Wiley Online Library
This is the first part of a two‐part study to investigate the cellular distribution and temporal
regulation of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole‐propionic acid receptor (AMPAR) …

Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons

CF Poulsen, TA Simeone, TE Maar… - Neurochemical …, 2004 - Springer
The effect of the antiepileptic drug topiramate on Ca 2+ uptake through (RS)-2-amino-3-(3-
hydroxy-5-methylisoxazol-4-yl) propionate (AMPA) and kainate (KA) receptors was …

AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3‐kinase‐dependent activation in extracellular signal‐regulated …

X Wu, D Zhu, X Jiang, P Okagaki… - Journal of …, 2004 - Wiley Online Library
The signal transduction and molecular mechanisms underlying α‐amino‐3‐hydroxy‐5‐
methyl‐4‐isoxazole propionate (AMPA)‐mediated neuroprotection are unknown. In the …

[HTML][HTML] Toll-like Receptor 4 signaling in neurons enhances calcium-permeable α-Amino-3-Hydroxy-5-Methyl-4-isoxazolepropionic acid receptor currents and drives …

AA Korgaonkar, Y Li, D Sekhar… - Annals of …, 2020 - escholarship.org
ObjectiveTraumatic brain injury is a major risk factor for acquired epilepsies, and
understanding the mechanisms underlying the early pathophysiology could yield viable …

Miniature synaptic currents become neurotoxic to chronically silenced neurons

I Fishbein, M Segal - Cerebral cortex, 2007 - academic.oup.com
When deprived of spontaneous ongoing network activity by chronic exposure to tetrodotoxin
(TTX), cultured cortical neurons retract their dendrites, lose dendritic spines, and degenerate …

AMPA Receptor–Mediated Neurotoxicity: Role of Ca2+ and Desensitization

A Frandsen, A Schousboe - Neurochemical research, 2003 - Springer
Glutamate-induced neurodegeneration is the result of excessive stimulation of the different
subtypes of glutamate receptors. With regard to the AMPA ((RS)-2-amino-3-(3-hydroxy-5 …

Sequential involvement of distinct glutamate receptors in domoic acid-induced neurotoxicity in rat mixed cortical cultures: effect of multiple dose/duration paradigms …

S Qiu, CW Pak, MC Currás-Collazo - Toxicological Sciences, 2006 - academic.oup.com
The increasing occurrence of poisoning accidents in marine animals caused by the amnesic
shellfish toxin, domoic acid (DOM), necessitates a better understanding of the factors …

Modulatory effect of glutamate GluR2 receptor on the caudal neurosecretory Dahlgren cells of the olive flounder, Paralichthys olivaceus

Z Lan, J Xu, Y Wang, W Lu - General and Comparative Endocrinology, 2018 - Elsevier
A neuromodulatory role for glutamate has been reported for magnocellular neuroendocrine
cells in mammalian hypothalamus. We examined the potential role of glutamate as a local …

[HTML][HTML] Developmental regulation of AMPA receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury: part II …

DM Talos, PL Follett, RD Folkerth… - The Journal of …, 2006 - ncbi.nlm.nih.gov
This report is the second of a two-part evaluation of developmental differences in α–amino-3-
hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor subunit expression in cell …

Dynorphin A toxicity in striatal neurons via an α-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor mechanism

RJ Goody, KM Martin, SM Goebel, KF Hauser - Neuroscience, 2003 - Elsevier
Dynorphin A (1-17) is an endogenous opioid peptide that is antinociceptive at physiological
concentrations, but in excess can elicit a number of pathological effects. Both κ-opioid and N …