[HTML][HTML] Multi-omics profiling for health

M Babu, M Snyder - Molecular & Cellular Proteomics, 2023 - ASBMB
The world has witnessed a steady rise in both non-infectious and infectious chronic
diseases, prompting a cross-disciplinary approach to understand and treating disease …

[HTML][HTML] The need for multi-omics biomarker signatures in precision medicine

M Olivier, R Asmis, GA Hawkins, TD Howard… - International journal of …, 2019 - mdpi.com
Recent advances in omics technologies have led to unprecedented efforts characterizing
the molecular changes that underlie the development and progression of a wide array of …

[HTML][HTML] Integrated omics: tools, advances and future approaches

BB Misra, C Langefeld, M Olivier… - Journal of molecular …, 2019 - jme.bioscientifica.com
With the rapid adoption of high-throughput omic approaches to analyze biological samples
such as genomics, transcriptomics, proteomics, and metabolomics, each analysis can …

–Omic and electronic health record big data analytics for precision medicine

PY Wu, CW Cheng, CD Kaddi… - IEEE Transactions …, 2016 - ieeexplore.ieee.org
Objective: Rapid advances of high-throughput technologies and wide adoption of electronic
health records (EHRs) have led to fast accumulation of–omic and EHR data. These …

Next-generation sequencing—an overview of the history, tools, and “Omic” applications

JK Kulski - Next generation sequencing-advances, applications …, 2016 - books.google.com
Next-generation sequencing (NGS) technologies using DNA, RNA, or methylation
sequencing have impacted enormously on the life sciences. NGS is the choice for large …

Translational bioinformatics in the era of real-time biomedical, health care and wellness data streams

K Shameer, MA Badgeley, R Miotto… - Briefings in …, 2017 - academic.oup.com
Monitoring and modeling biomedical, health care and wellness data from individuals and
converging data on a population scale have tremendous potential to improve understanding …

[HTML][HTML] The biomarker GlycA is associated with chronic inflammation and predicts long-term risk of severe infection

SC Ritchie, P Würtz, AP Nath, G Abraham… - Cell systems, 2015 - cell.com
The biomarker glycoprotein acetylation (GlycA) has been shown to predict risk of
cardiovascular disease and all-cause mortality. Here, we characterize biological processes …

Harnessing big data to advance treatment and understanding of pulmonary hypertension

CJ Rhodes, AJ Sweatt, BA Maron - Circulation research, 2022 - Am Heart Assoc
Pulmonary hypertension is a complex disease with multiple causes, corresponding to
phenotypic heterogeneity and variable therapeutic responses. Advancing understanding of …

[HTML][HTML] A review on computational systems biology of pathogen–host interactions

S Durmuş, T Çakır, A Özgür, R Guthke - Frontiers in microbiology, 2015 - frontiersin.org
Pathogens manipulate the cellular mechanisms of host organisms via pathogen–host
interactions (PHIs) in order to take advantage of the capabilities of host cells, leading to …

Role of polyphenols and carotenoids in endothelial dysfunction: An overview from classic to innovative biomarkers

N Di Pietro, MPA Baldassarre, A Cichelli… - Oxidative Medicine …, 2020 - Wiley Online Library
Nowadays, the dramatically increased prevalence of metabolic diseases, such as obesity
and diabetes mellitus and their related complications, including endothelial dysfunction and …