Synthetic and non-synthetic cannabinoid drugs and their adverse effects-a review from public health prospective

K Cohen, AM Weinstein - Frontiers in public health, 2018 - frontiersin.org
There is a growing use of novel psychoactive substances containing synthetic cannabinoids.
Synthetic cannabinoid products have effects similar to those of natural cannabis, yet, these …

Synthetic cathinone and cannabinoid designer drugs pose a major risk for public health

AM Weinstein, P Rosca, L Fattore… - Frontiers in psychiatry, 2017 - frontiersin.org
As part of an increasing worldwide use of designer drugs, recent use of compounds
containing cathinones and synthetic cannabinoids is especially prevalent. Here, we …

Gray and white matter morphology in substance use disorders: a neuroimaging systematic review and meta-analysis

V Pando-Naude, S Toxto, S Fernandez-Lozano… - Translational …, 2021 - nature.com
Substance use disorders (SUDs) are characterized by a compulsion to seek and consume
one or more substances of abuse, with a perceived loss of control and a negative emotional …

The thalamus in drug addiction: from rodents to humans

AS Huang, JA Mitchell, SN Haber… - … of the Royal …, 2018 - royalsocietypublishing.org
Impairments in response inhibition and salience attribution (iRISA) have been proposed to
underlie the clinical symptoms of drug addiction as mediated by cortico-striatal-thalamo …

Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 …

SD Lichenstein, N Manco, LM Cope, L Egbo… - …, 2022 - nature.com
Cannabis use peaks in adolescence, and adolescents may be more vulnerable to the neural
effects of cannabis and cannabis-related harms due to ongoing brain development during …

Cannabis, cannabinoids, and brain morphology: a review of the evidence

Y Chye, R Kirkham, V Lorenzetti, E McTavish… - Biological Psychiatry …, 2021 - Elsevier
Cannabis and cannabinoid-based products are increasingly being accepted and
commodified globally. Yet there is currently limited understanding of the effect of the varied …

Synthetic cannabinoids: psychopharmacology, clinical aspects, psychotic onset

G Martinotti, R Santacroce, D Papanti… - CNS & Neurological …, 2017 - ingentaconnect.com
Background: Synthetic Cannabinoids (SC) are the widest and most diffused class of Novel
Psychoactive Substances. The short-and long-term health risks associated with the …

Pharmacology and adverse effects of new psychoactive substances: synthetic cannabinoid receptor agonists

EY Chung, HJ Cha, HK Min, J Yun - Archives of Pharmacal Research, 2021 - Springer
Over the last decade, new psychoactive substances (NPS) have continuously been the
focus of the international society since their emergence on the illicit drug market. NPS can …

The expression analyses of GSK3B, VEGF, ANG1, and ANG2 in human brain microvascular endothelial cells treated with the synthetic cannabinoid XLR-11

ALE Laith, S Alahmad - Gene, 2023 - Elsevier
The endocannabinoid system receptors, cannabinoid receptors type-1 (CBR-1) and− 2
(CBR-2), are implicated in several behavioral and cognitive processes. Many studies have …

Adolescent substance use initiation and long-term neurobiological outcomes: insights, challenges and opportunities

OD Boer, H El Marroun, RL Muetzel - Molecular Psychiatry, 2024 - nature.com
The increased frequency of risk taking behavior combined with marked neuromaturation has
positioned adolescence as a focal point of research into the neural causes and …