Cancer is a major disease worldwide. Despite progress in cancer therapy, conventional
cytotoxic therapies lead to unsatisfactory long-term survival, mainly related to development …

Docosahexaenoic acid (DHA) with 22-carbons and 6 double bonds is the extreme example
of an ω-3 polyunsaturated fatty acid (PUFA). DHA has strong medical implications since its …

Tumor specific drug delivery has become increasingly interesting in cancer therapy, as the
use of chemotherapeutics is often limited due to severe side effects. Conventional drug …

High plasma levels of fatty acids occur in a variety of metabolic diseases. Cellular effects of
fatty acid overload resulting in negative cellular responses (lipotoxicity) are often studied in …

The physiological resolution of a well-orchestrated inflammatory response is essential to
maintain homeostasis. Therefore, gaining a comprehensive understanding in molecular …

With 22 carbons and 6 double bonds docosahexaenoic acid (DHA) is the longest and most
unsaturated fatty acid commonly found in membranes. It represents the extreme example of …

Background The present study sought to further investigate the in vitro and in vivo anticancer
effects of a representative omega-3 fatty acid, docosahexaenoic acid (DHA), with a focus on …

Nanomedicine as a field has emerged from the early success of nanoparticle-based drug
delivery systems, in particular for treatment of cancer, and the advances made in nano-and …

Injury triggers inflammatory responses and tissue repair. Several treatments are currently in
use to accelerate healing; however, more efficient formulations are still needed for specific …

Background: Lipid emulsions for parenteral nutrition commercially available are mainly
composed of long-chain triacylglycerol containing a high proportion of ω-6 polyunsaturated …