Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis

H Li, XH Yu, X Ou, XP Ouyang, CK Tang - Progress in lipid research, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

[HTML][HTML] A new perspective on lipid research in age-related macular degeneration

EM van Leeuwen, E Emri, BMJ Merle, JM Colijn… - Progress in retinal and …, 2018 - Elsevier
There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …

Omega-3 fatty acids, hepatic lipid metabolism, and nonalcoholic fatty liver disease

E Scorletti, CD Byrne - Annual review of nutrition, 2013 - annualreviews.org
Long-chain omega-3 fatty acids belong to a family of polyunsaturated fatty acids that are
known to have important beneficial effects on metabolism and inflammation. Such effects …

[HTML][HTML] Free radical biology for medicine: learning from nonalcoholic fatty liver disease

G Serviddio, F Bellanti, G Vendemiale - Free Radical Biology and Medicine, 2013 - Elsevier
Reactive oxygen species, when released under controlled conditions and limited amounts,
contribute to cellular proliferation, senescence, and survival by acting as signaling …

A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis

YH Han, KO Shin, JY Kim, DB Khadka… - The Journal of …, 2019 - Am Soc Clin Investig
Retinoic acid–related orphan receptor α (RORα) is considered a key regulator of
polarization in liver macrophages that is closely related to nonalcoholic steatohepatitis …

ABCG5/ABCG8 in cholesterol excretion and atherosclerosis

XH Yu, K Qian, N Jiang, XL Zheng, FS Cayabyab… - Clinica Chimica …, 2014 - Elsevier
Cholesterol is essential for the growth and function of all mammalian cells, but abnormally
increased blood cholesterol is a major risk factor for atherosclerotic cardiovascular disease …

Lipid oxidation products in the pathogenesis of non-alcoholic steatohepatitis

F Bellanti, R Villani, A Facciorusso… - Free Radical Biology …, 2017 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the major public health challenge for
hepatologists in the twenty-first century. NAFLD comprises a histological spectrum ranging …

Anti-Obesity Effect of Standardized Extract of Microalga Phaeodactylum tricornutum Containing Fucoxanthin

SY Koo, JH Hwang, SH Yang, JI Um, KW Hong, K Kang… - Marine drugs, 2019 - mdpi.com
Fucoxanthin (FX), a marine carotenoid found in macroalgae and microalgae, exhibits
several beneficial effects to health. The anti-obesity activity of FX is well documented, but FX …

The transplantation of ω3 PUFA–Altered Gut microbiota of FAT-1 mice to wild-type littermates prevents obesity and associated metabolic disorders

C Bidu, Q Escoula, S Bellenger, A Spor, M Galan… - Diabetes, 2018 - Am Diabetes Assoc
Altering the gut microbiome may be beneficial to the host and recently arose as a promising
strategy to manage obesity. Here, we investigated the relative contribution of ω3 …

[HTML][HTML] Prevention of colitis-induced liver oxidative stress and inflammation in a transgenic mouse model with increased omega-3 polyunsaturated fatty acids

N Rohwer, J Jelleschitz, A Höhn, D Weber, AA Kühl… - Redox Biology, 2023 - Elsevier
Inflammatory bowel disease (IBD) is an immune-mediated gut dysfunction, which might also
be associated with an inflammatory phenotype in the liver. It is known that the nutritional …