Recent updates on mechanisms of resistance to 5-fluorouracil and reversal strategies in colon cancer treatment

S Azwar, HF Seow, M Abdullah, M Faisal Jabar… - Biology, 2021 - mdpi.com
Simple Summary Acquired resistance to chemotherapy by cancer cells is the predominant
factor in chemotherapy failure, which ultimately leads to disease progression and death …

Pharmacological and Antioxidant Activities of Rhus coriaria L. (Sumac)

H Alsamri, K Athamneh, G Pintus, AH Eid, R Iratni - Antioxidants, 2021 - mdpi.com
Rhus coriaria L.(Anacardiaceae), commonly known as sumac, is a commonly used spice,
condiment, and flavoring agent, especially in the Mediterranean region. Owing to its …

Traditional use, phytochemistry, toxicology, and pharmacology of Origanum majorana L.

A Bouyahya, I Chamkhi, T Benali… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Origanum majorana L., is an aromatic and medicinal plant
distributed in different parts of Mediterranean countries. This species is widely used in …

Phytochemical constituents, biological activities, and health‐promoting effects of the genus Origanum

M Sharifi‐Rad, Y Berkay Yılmaz, G Antika… - Phytotherapy …, 2021 - Wiley Online Library
Origanum species are mostly distributed around the Mediterranean, Euro‐Siberian, and Iran‐
Siberian regions. Since time immemorial, the genus has popularly been used in Southern …

Andrographolide suppresses non-small-cell lung cancer progression through induction of autophagy and antitumor immune response

XR Wang, ZB Jiang, C Xu, WY Meng, P Liu… - Pharmacological …, 2022 - Elsevier
Despite recent advances in diagnosis and therapeutic strategies, treatment of non-small-cell
lung cancer (NSCLC) remains unsatisfactory in terms of prognosis. Andrographolide (AD), a …

Origanum majorana Essential Oil Triggers p38 MAPK-Mediated Protective Autophagy, Apoptosis, and Caspase-Dependent Cleavage of P70S6K in Colorectal …

K Athamneh, A Alneyadi, H Alsamri, A Alrashedi… - Biomolecules, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most common type of cancer in terms of incidence and
mortality worldwide. Here we have investigated the anti-colon cancer potential of Origanum …

Autophagy as a molecular target of quercetin underlying its protective effects in human diseases

M Ashrafizadeh, Z Ahmadi, T Farkhondeh… - … of Physiology and …, 2022 - Taylor & Francis
Autophagy, known as a “self-eating” process, is associated with degradation of aged or
damaged components and organelles. Generally, autophagy is a survival mechanism that …

An in vitro evaluation of the molecular mechanisms of action of medical plants from the Lamiaceae family as effective sources of active compounds against human …

P Sitarek, A Merecz-Sadowska, T Śliwiński, R Zajdel… - Cancers, 2020 - mdpi.com
Simple Summary Plants have been used in folk medicine for thousands of years. The
Lamiaceae family is one of the largest families of flowering plants and includes a wide …

Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells

A AlKahlout, M Fardoun, J Mesmar, R Abdallah… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is the leading cause of cancer-related deaths among women. Among breast
cancer types, triple negative breast cancer (TNBC) is the most aggressive, and is resistant to …

The impact of herbal infusion consumption on oxidative stress and cancer: the good, the bad, the misunderstood

WH Talib, IA Al-Ataby, AI Mahmod, S Jawarneh… - Molecules, 2020 - mdpi.com
The release of reactive oxygen species (ROS) and oxidative stress is associated with the
development of many ailments, including cardiovascular diseases, diabetes and cancer …