Discovery of digestive enzymes in carnivorous plants with focus on proteases

R Ravee, FIM Salleh, HH Goh - PeerJ, 2018 - peerj.com
Background Carnivorous plants have been fascinating researchers with their unique
characters and bioinspired applications. These include medicinal trait of some carnivorous …

Omics approaches in uncovering molecular evolution and physiology of botanical carnivory

A Baharin, TY Ting, HH Goh - Plants, 2023 - mdpi.com
Systems biology has been increasingly applied with multiple omics for a holistic
comprehension of complex biological systems beyond the reductionist approach that …

Sequence characterization and molecular modeling of clinically relevant variants of the SARS-CoV-2 main protease

TJ Cross, GR Takahashi, EM Diessner, MG Crosby… - Biochemistry, 2020 - ACS Publications
The SARS-CoV-2 main protease (M pro) is essential to viral replication and cleaves highly
specific substrate sequences, making it an obvious target for inhibitor design. However, as …

Comparative exploratory analysis of intrinsically disordered protein dynamics using machine learning and network analytic methods

G Grazioli, RW Martin, CT Butts - Frontiers in molecular biosciences, 2019 - frontiersin.org
Simulations of intrinsically disordered proteins (IDPs) pose numerous challenges to
comparative analysis, prominently including highly dynamic conformational states and a …

Highly scalable maximum likelihood and conjugate Bayesian inference for ERGMs on graph sets with equivalent vertices

F Yin, CT Butts - Plos one, 2022 - journals.plos.org
The exponential family random graph modeling (ERGM) framework provides a highly
flexible approach for the statistical analysis of networks (ie, graphs). As ERGMs with dyadic …

Finite mixtures of ERGMS for modeling ensembles of networks

F Yin, W Shen, CT Butts - Bayesian Analysis, 2022 - projecteuclid.org
Finite Mixtures of ERGMs for Modeling Ensembles of Networks Page 1 Bayesian Analysis (2022)
17, Number 4, pp. 1153–1191 Finite Mixtures of ERGMs for Modeling Ensembles of Networks …

Biochemical and antifungal characteristics of recombinant class I chitinase from Drosera rotundifolia

M Rajninec, M Jopcik, M Danchenko… - International Journal of …, 2020 - Elsevier
DrChit is class I chitinase involved in the digestion of insect prey of Drosera rotundifolia
plants. Herein, we cloned the DrChit-S open reading frame lacking the 5′-sequence coding …

Network Hamiltonian models for unstructured protein aggregates, with application to γD-Crystallin

EM Diessner, JA Freites, DJ Tobias… - The Journal of Physical …, 2023 - ACS Publications
Network Hamiltonian models (NHMs) are a framework for topological coarse-graining of
protein–protein interactions, in which each node corresponds to a protein, and edges are …

Neural upscaling from residue-level protein structure networks to atomistic structures

VT Duong, EM Diessner, G Grazioli, RW Martin… - Biomolecules, 2021 - mdpi.com
Coarse-graining is a powerful tool for extending the reach of dynamic models of proteins
and other biological macromolecules. Topological coarse-graining, in which biomolecules …

The Droserasin 1 PSI: A Membrane-Interacting Antimicrobial Peptide from the Carnivorous Plant Drosera capensis

MA Sprague-Piercy, JC Bierma, MG Crosby… - Biomolecules, 2020 - mdpi.com
The Droserasins, aspartic proteases from the carnivorous plant Drosera capensis, contain a
100-residue plant-specific insert (PSI) that is post-translationally cleaved and independently …