Environmental arsenic exposure and its contribution to human diseases, toxicity mechanism and management

MS Rahaman, MM Rahman, N Mise, MT Sikder… - Environmental …, 2021 - Elsevier
Arsenic is a well-recognized environmental contaminant that occurs naturally through
geogenic processes in the aquifer. More than 200 million people around the world are …

Arsenic and human health effects: A review

KSM Abdul, SS Jayasinghe, EPS Chandana… - Environmental …, 2015 - Elsevier
Arsenic (As) is ubiquitous in nature and humans being exposed to arsenic via atmospheric
air, ground water and food sources are certain. Major sources of arsenic contamination …

[PDF][PDF] Preventing disease through healthy environments: inadequate or excess fluoride: a major public health concern

World Health Organization - 2019 - apps.who.int
Fluoride intake has both beneficial effects–in reducing the incidence of dental caries–and
negative effects–in causing tooth enamel and skeletal fluorosis following prolonged …

p62 links autophagy and Nrf2 signaling

T Jiang, B Harder, MR De La Vega, PK Wong… - Free Radical Biology …, 2015 - Elsevier
Abstract The Nrf2-Keap1-ARE pathway is a redox and xenobiotic sensitive signaling axis
that functions to protect cells against oxidative stress, environmental toxicants, and harmful …

Contamination and health risk assessment of arsenic and chromium in coastal sediments of Al-Khobar area, Arabian Gulf, Saudi Arabia

T Alharbi, K Al-Kahtany, HE Nour, S Giacobbe… - Marine Pollution …, 2022 - Elsevier
The contamination and health risks by arsenic and chromium in the Al-Khobar coastal area,
Arabian Gulf, have been assessed by examining 29 samples of surface sediment. Several …

Trace elements in human nutrition (II)–an update

A Mehri - International journal of preventive medicine, 2020 - journals.lww.com
The dietary requirement for an essential trace element is an intake level which meets a
specified criterion for adequacy and thereby minimizes risk of nutrient deficiency or excess …

Neurotoxicity linked to dysfunctional metal ion homeostasis and xenobiotic metal exposure: redox signaling and oxidative stress

C Garza-Lombó, Y Posadas, L Quintanar… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Essential metals such as copper, iron, manganese, and zinc play a role as
cofactors in the activity of a wide range of processes involved in cellular homeostasis and …

[HTML][HTML] Connections between endoplasmic reticulum stress-associated unfolded protein response, mitochondria, and autophagy in arsenic-induced carcinogenesis

P Wadgaonkar, F Chen - Seminars in cancer biology, 2021 - Elsevier
Arsenic exposure in contaminated drinking water is a global health issue, as more than 200
million people are affected globally. Arsenic has been known to cause skin, liver, lung …

Arsenic-induced neurotoxicity: a mechanistic appraisal

C Garza-Lombó, A Pappa, MI Panayiotidis… - JBIC Journal of …, 2019 - Springer
Arsenic is a metalloid found in groundwater as a byproduct of soil/rock erosion and industrial
and agricultural processes. This xenobiotic elicits its toxicity through different mechanisms …

Epigenetics and the Developmental Origins of Health and Disease: Parental environment signalling to the epigenome, critical time windows and sculpting the adult …

S Safi-Stibler, A Gabory - Seminars in cell & developmental biology, 2020 - Elsevier
Abstract The literature about Developmental Origins of Health and Disease (DOHaD)
studies is considerably growing. Maternal and paternal environment, during all the …