Leishmaniasis is a disease of the subtropical and tropical spheres of the earth and has
various clinical manifestations. The different form of leishmaniasis includes cutaneous …

Ficolins are innate pattern recognition receptors (PRR) and play integral roles within the
innate immune response to numerous pathogens throughout the circulation, as well as …

Visceral leishmaniasis (VL) is a neglected and highly lethal disease. VL is endemic in South
American countries, with Brazil being responsible for 96% of the cases. In this continent, VL …

Genetic variability in the complement system and its association with disease has been
known for more than 50 years, but only during the last decade have we begun to understand …

Visceral Leishmaniasis is an infectious disease that affects mainly humans and dogs, with
the latter being important reservoirs of the parasite. Conversely, cats are naturally resistant …

Introducción: El sistema del complemento puede ser activado por tres vías: clásica,
alternativa y de las lectinas, esta última en fase de estudio para su completamiento …

The aim of this study was to examine the association of single-nucleotide polymorphisms
(SNPs) in the gene encoding ficolin-2 protein (FCN2 gene) at positions-986 (rs17514136) …

Ficolins are pattern recognition molecules that are involved in innate immune defense.
Ficonin-2 (FCN2) has a specific affinity for lipoteichoic acid present in the cell wall of …

L-ficolin encoded by FCN2 gene is a crucial factor of defence against infection in humans.
We studied the prevalence of the two common variants (rs17549193 and rs7851696) in …

Visceral Leishmaniasis (VL), caused by Leishmania donovani is endemic in the Indian sub-
continent. Mannose-binding Lectin (MBL) is a complement lectin protein that binds to the …