[HTML][HTML] Exosomes, a new star for targeted delivery

H Chen, L Wang, X Zeng, H Schwarz… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing
numerous biological molecules including nucleic acids, proteins and lipids, which are …

[HTML][HTML] Exosome engineering: Current progress in cargo loading and targeted delivery

S Fu, Y Wang, X Xia, JC Zheng - NanoImpact, 2020 - Elsevier
Exosomes, a class of small bilayer vesicles derived from virtually all eukaryotic cells, have
been exploited as a promising natural delivery platform due to their low toxicity, excellent …

[HTML][HTML] Exosome theranostics: biology and translational medicine

C He, S Zheng, Y Luo, B Wang - Theranostics, 2018 - ncbi.nlm.nih.gov
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules,
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …

[HTML][HTML] Designer exosomes: a new platform for biotechnology therapeutics

D Jafari, S Shajari, R Jafari, N Mardi, H Gomari, F Ganji… - BioDrugs, 2020 - Springer
Desirable features of exosomes have made them a suitable manipulative platform for
biomedical applications, including targeted drug delivery, gene therapy, cancer diagnosis …

[HTML][HTML] Extracellular vesicles: exosomes and microvesicles, integrators of homeostasis

PD Stahl, G Raposo - Physiology, 2019 - journals.physiology.org
Abstract Extracellular vesicles (EVs), cell-derived membrane structures, are secreted after
fusion of endosomes with the plasma membrane (exosomes) or shed from the plasma …

Approaches to surface engineering of extracellular vesicles

M Richter, P Vader, G Fuhrmann - Advanced drug delivery reviews, 2021 - Elsevier
Extracellular vesicles (EVs) are cell-derived nanoparticles that are important mediators in
intercellular communication. This function makes them auspicious candidates for therapeutic …

Human mesenchymal stem cell derived exosomes alleviate type 2 diabetes mellitus by reversing peripheral insulin resistance and relieving β-cell destruction

Y Sun, H Shi, S Yin, C Ji, X Zhang, B Zhang, P Wu… - ACS …, 2018 - ACS Publications
Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue
regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to …

[HTML][HTML] Functional exosome-mediated co-delivery of doxorubicin and hydrophobically modified microRNA 159 for triple-negative breast cancer therapy

C Gong, J Tian, Z Wang, Y Gao, X Wu, X Ding… - Journal of …, 2019 - Springer
Exosomes (Exo) hold great promise as endogenous nanocarriers that can deliver biological
information between cells. However, Exo are limited in terms of their abilities to target …

[HTML][HTML] Exosomal DMBT1 from human urine-derived stem cells facilitates diabetic wound repair by promoting angiogenesis

CY Chen, SS Rao, L Ren, XK Hu, YJ Tan, Y Hu… - Theranostics, 2018 - ncbi.nlm.nih.gov
Chronic non-healing wounds represent one of the most common complications of diabetes
and need advanced treatment strategies. Exosomes are key mediators of cell paracrine …

Long noncoding RNA CCAL transferred from fibroblasts by exosomes promotes chemoresistance of colorectal cancer cells

X Deng, H Ruan, X Zhang, X Xu, Y Zhu… - … journal of cancer, 2020 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are involved in the pathology of colorectal cancer (CRC).
Current efforts to eradicate CRC predominantly focused on targeting the proliferation of …