Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel

MS Hirsch, HF Günthard, JM Schapiro… - Clinical Infectious …, 2008 - academic.oup.com
Resistance to antiretroviral drugs remains an important limitation to successful human
immunodeficiency virus type 1 (HIV-1) therapy. Resistance testing can improve treatment …

[PDF][PDF] Temporal changes in the epidemiology of transmission of drug-resistant HIV-1 across the world

D Frentz, CA Boucher, DA Van De Vijver - AIDs Rev, 2012 - academia.edu
A substantial number of studies have been performed across the world to determine
transmitted drug resistance. Large variations between different parts of the world can be …

Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection

SJ Little, SDW Frost, JK Wong, DM Smith… - Journal of …, 2008 - Am Soc Microbiol
Following interruption of antiretroviral therapy among individuals with acquired drug
resistance, preexisting drug-sensitive virus emerges relatively rapidly. In contrast, wild-type …

HIV-1 reverse transcriptase inhibitor resistance mutations and fitness: a view from the clinic and ex vivo

J Martinez-Picado, MA Martínez - Virus research, 2008 - Elsevier
Genetic diversity plays a key role in human immunodeficiency virus (HIV) adaptation,
providing a mechanism to escape host immune responses and develop resistance to …

Transmission of HIV-1 drug resistance in Switzerland: a 10-year molecular epidemiology survey

S Yerly, V von Wyl, B Ledergerber, J Böni… - Aids, 2007 - journals.lww.com
Objectives: Representative prevalence data of transmitted drug-resistant HIV-1 are essential
to establish accurate guidelines addressing resistance testing and first-line treatments …

Cohort profile: the Danish HIV cohort study

N Obel, FN Engsig, LD Rasmussen… - International journal …, 2009 - academic.oup.com
Shortly after AIDS was recognized in USA, the first cases were diagnosed in Denmark. 1, 2
Today Denmark has a population of 5.3 million citizens and the prevalence of HIV infection …

Transmission of HIV-1 minority-resistant variants and response to first-line antiretroviral therapy

O Peuchant, R Thiébaut, S Capdepont… - Aids, 2008 - journals.lww.com
Background: The transmission of drug-resistant HIV-1 can impair the virological response to
antiretroviral therapy. Minority-resistant variants have been detected in acute …

Drug resistance in the HIV-1-infected paediatric population worldwide: a systematic review

P Rojas Sánchez, A Holguín - Journal of Antimicrobial …, 2014 - academic.oup.com
Background Drug resistance monitoring of the paediatric HIV-1-infected population is
required to optimize treatment success and preserve future treatment options. Objectives To …

Prevalence of antiretroviral drug resistance and resistance-associated mutations in antiretroviral therapy-naive HIV-infected individuals from 40 United States cities

L Ross, ML Lim, Q Liao, B Wine, AE Rodriguez… - HIV clinical …, 2007 - Taylor & Francis
Background: Transmission of drug-resistant HIV strains to antiretroviral therapy (ART)-naïve
subjects can negatively impact therapy response. As treatment strategies and utilization of …

Stable frequency of HIV-1 transmitted drug resistance in patients at the time of primary infection over 1996–2006 in France

ML Chaix, D Descamps, M Wirden, L Bocket… - Aids, 2009 - journals.lww.com
Background: Transmission of drug-resistant variants is influenced by several factors,
including the HIV-1 RNA levels in HIV-1-infected patients. Our study describes the …