A transcriptome constructed from short-read RNA sequencing (RNA-seq) is an easily
attainable proxy catalog of protein-coding genes when genome assembly is unnecessary …

As the body continues to grow and age, it becomes essential to maintain a balance between
living and dying cells. Macrophages and dendritic cells play a central role in discriminating …

Tropane alkaloids from nightshade plants are neurotransmitter inhibitors that are used for
treating neuromuscular disorders and are classified as essential medicines by the World …

Regeneration is the holy grail of tissue repair, but skin injury typically yields fibrotic, non-
functional scars. Developing pro-regenerative therapies requires rigorous understanding of …

Evidence is accumulating to challenge the paradigm that biogenic methanogenesis,
considered a strictly anaerobic process, is exclusive to archaea. We demonstrate that …

Salamanders serve as important tetrapod models for developmental, regeneration and
evolutionary studies. An extensive molecular toolkit makes the Mexican axolotl (Ambystoma …

An outstanding mystery in biology is why some species, such as the axolotl, can regenerate
tissues whereas mammals cannot. Here, we demonstrate that rapid activation of protein …

Regeneration of complex multi-tissue structures, such as limbs, requires the coordinated
effort of multiple cell types. In axolotl limb regeneration, the wound epidermis and blastema …

Vertebrates harbor recognizably orthologous gene complements but vary 100-fold in
genome size. How chromosomal organization scales with genome expansion is unclear …

Indirect development with an intermediate larva exists in all major animal lineages, which
makes larvae central to most scenarios of animal evolution,,,,,,,,–. Yet how larvae evolved …