[HTML][HTML] Type I and type III interferons–induction, signaling, evasion, and application to combat COVID-19
A Park, A Iwasaki - Cell host & microbe, 2020 - cell.com
Coronavirus disease 2019 (COVID-19) is a global pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Without approved antiviral therapeutics …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Without approved antiviral therapeutics …
MERS, SARS and other coronaviruses as causes of pneumonia
Y Yin, RG Wunderink - Respirology, 2018 - Wiley Online Library
Human coronaviruses (HCoVs) have been considered to be relatively harmless respiratory
pathogens in the past. However, after the outbreak of the severe acute respiratory syndrome …
pathogens in the past. However, after the outbreak of the severe acute respiratory syndrome …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling
Y Zheng, MW Zhuang, L Han, J Zhang… - Signal transduction and …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has quickly spread worldwide and has affected …
syndrome coronavirus 2 (SARS-CoV-2), has quickly spread worldwide and has affected …
Remdesivir inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the novel viral disease COVID-19. With no approved therapies, this pandemic illustrates the …
the novel viral disease COVID-19. With no approved therapies, this pandemic illustrates the …
Vascular disease and thrombosis in SARS-CoV-2-infected rhesus macaques
The COVID-19 pandemic has led to extensive morbidity and mortality throughout the world.
Clinical features that drive SARS-CoV-2 pathogenesis in humans include inflammation and …
Clinical features that drive SARS-CoV-2 pathogenesis in humans include inflammation and …
[HTML][HTML] Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy
Detailed knowledge of the molecular biology of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection is crucial for understanding of viral replication, host …
coronavirus 2 (SARS-CoV-2) infection is crucial for understanding of viral replication, host …
[HTML][HTML] SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon
M Shemesh, TE Aktepe, JM Deerain, JL McAuley… - PLoS …, 2021 - journals.plos.org
Type I Interferons (IFN-Is) are a family of cytokines which play a major role in inhibiting viral
infection. Resultantly, many viruses have evolved mechanisms in which to evade the IFN-I …
infection. Resultantly, many viruses have evolved mechanisms in which to evade the IFN-I …
Master regulator analysis of the SARS-CoV-2/human interactome
PH Guzzi, D Mercatelli, C Ceraolo… - Journal of clinical medicine, 2020 - mdpi.com
The recent epidemic outbreak of a novel human coronavirus called SARS-CoV-2 causing
the respiratory tract disease COVID-19 has reached worldwide resonance and a global …
the respiratory tract disease COVID-19 has reached worldwide resonance and a global …
[HTML][HTML] A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
VD Menachery, BL Yount, K Debbink, S Agnihothram… - Nature medicine, 2015 - nature.com
The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle
East respiratory syndrome (MERS)-CoV underscores the threat of cross-species …
East respiratory syndrome (MERS)-CoV underscores the threat of cross-species …
[HTML][HTML] Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19
Abstract Coronavirus disease 2019 (COVID-19) is especially severe in aged populations.
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are …
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are …