[HTML][HTML] The role of M1/M2 macrophage polarization in rheumatoid arthritis synovitis
M Cutolo, R Campitiello, E Gotelli… - Frontiers in …, 2022 - frontiersin.org
Innate and adaptive immunity represent a harmonic counterbalanced system involved in the
induction, progression, and possibly resolution of the inflammatory reaction that characterize …
induction, progression, and possibly resolution of the inflammatory reaction that characterize …
Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …
A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
Abstract The COVID-19-, SARS-and MERS-related coronaviruses share many genomic and
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …
[HTML][HTML] Macrophage-osteoclast associations: origin, polarization, and subgroups
Y Sun, J Li, X Xie, F Gu, Z Sui, K Zhang… - Frontiers in …, 2021 - frontiersin.org
Cellular associations in the bone microenvironment are involved in modulating the balance
between bone remodeling and resorption, which is necessary for maintaining a normal bone …
between bone remodeling and resorption, which is necessary for maintaining a normal bone …
pH/NIR-responsive and self-healing coatings with bacteria killing, osteogenesis, and angiogenesis performances on magnesium alloy
Y Zhao, P He, J Yao, M Li, B Wang, L Han, Z Huang… - Biomaterials, 2023 - Elsevier
Although biodegradable polymer coatings can impede corrosion of magnesium (Mg)-based
orthopedic implants, they are prone to excessive degradation and accidental scratching in …
orthopedic implants, they are prone to excessive degradation and accidental scratching in …
[HTML][HTML] CCL2/CCR2 signaling in cancer pathogenesis
Q Hao, JV Vadgama, P Wang - Cell Communication and Signaling, 2020 - Springer
Chemokines are a family of small cytokines, which guide a variety of immune/inflammatory
cells to the site of tumor in tumorigenesis. A dysregulated expression of chemokines is …
cells to the site of tumor in tumorigenesis. A dysregulated expression of chemokines is …
[HTML][HTML] Molecular and cellular heterogeneity in rheumatoid arthritis: mechanisms and clinical implications
Rheumatoid arthritis is an autoimmune disease that exhibits significant clinical
heterogeneity. There are various treatments for rheumatoid arthritis, including disease …
heterogeneity. There are various treatments for rheumatoid arthritis, including disease …
Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium
The therapeutic potential of liposomes to deliver drugs into inflamed tissue is well
documented. Liposomes are believed to largely transport drugs into inflamed joints by …
documented. Liposomes are believed to largely transport drugs into inflamed joints by …
[HTML][HTML] Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention
JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
With the objective of linking early findings relating to the novel SARS-CoV-2 coronavirus
with potentially informative findings from prior research literature and to promote …
with potentially informative findings from prior research literature and to promote …
[HTML][HTML] Critical role of synovial tissue–resident macrophage and fibroblast subsets in the persistence of joint inflammation
Rheumatoid arthritis (RA) is a chronic prototypic immune-mediated inflammatory disease
which is characterized by persistent synovial inflammation, leading to progressive joint …
which is characterized by persistent synovial inflammation, leading to progressive joint …
[HTML][HTML] MicroRNA-mediated epigenetic regulation of rheumatoid arthritis susceptibility and pathogenesis
C Chang, L Xu, R Zhang, Y Jin, P Jiang, K Wei… - Frontiers in …, 2022 - frontiersin.org
MicroRNAs (miRNAs) play crucial roles in regulating the transcriptome and development of
rheumatoid arthritis (RA). Currently, a comprehensive map illustrating how miRNAs regulate …
rheumatoid arthritis (RA). Currently, a comprehensive map illustrating how miRNAs regulate …