Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
Innate metabolic responses against viral infections
CS Palmer - Nature Metabolism, 2022 - nature.com
Metabolic adaptation to viral infections critically determines the course and manifestations of
disease. At the systemic level, a significant feature of viral infection and inflammation that …
disease. At the systemic level, a significant feature of viral infection and inflammation that …
[HTML][HTML] Serotonin reduction in post-acute sequelae of viral infection
AC Wong, AS Devason, IC Umana, TO Cox… - Cell, 2023 - cell.com
Post-acute sequelae of COVID-19 (PASC," Long COVID") pose a significant global health
challenge. The pathophysiology is unknown, and no effective treatments have been found to …
challenge. The pathophysiology is unknown, and no effective treatments have been found to …
CAR-T cell therapy-related cytokine release syndrome and therapeutic response is modulated by the gut microbiome in hematologic malignancies
Immunotherapy utilizing chimeric antigen receptor T cell (CAR-T) therapy holds promise for
hematologic malignancies, however, response rates and associated immune-related …
hematologic malignancies, however, response rates and associated immune-related …
Metabolomics study of COVID-19 patients in four different clinical stages
A Valdés, LO Moreno, SR Rello, A Orduña… - Scientific reports, 2022 - nature.com
Abstract SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the coronavirus
strain causing the respiratory pandemic COVID-19 (coronavirus disease 2019). To …
strain causing the respiratory pandemic COVID-19 (coronavirus disease 2019). To …
Gut and airway microbiota dysbiosis and their role in COVID-19 and long-COVID
The gut microbiota plays a crucial role in human health and disease. Gut dysbiosis is known
to be associated with increased susceptibility to respiratory diseases and modifications in …
to be associated with increased susceptibility to respiratory diseases and modifications in …
COVIDomics: The proteomic and metabolomic signatures of COVID-19
M Costanzo, M Caterino, R Fedele, A Cevenini… - International journal of …, 2022 - mdpi.com
Omics-based technologies have been largely adopted during this unprecedented global
COVID-19 pandemic, allowing the scientific community to perform research on a large scale …
COVID-19 pandemic, allowing the scientific community to perform research on a large scale …
Metabolomics in the Diagnosis and Prognosis of COVID-19
MR Hasan, M Suleiman, A Perez-Lopez - Frontiers in Genetics, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) pandemic triggered an unprecedented global effort
in developing rapid and inexpensive diagnostic and prognostic tools. Since the genome of …
in developing rapid and inexpensive diagnostic and prognostic tools. Since the genome of …
[HTML][HTML] The safety and anti-ageing effects of nicotinamide mononucleotide in human clinical trials: an update
Q Song, X Zhou, K Xu, S Liu, X Zhu, J Yang - Advances in nutrition, 2023 - Elsevier
The importance of nicotinamide adenine dinucleotide (NAD+) in human physiology is well
recognized. As the NAD+ concentration in human skin, blood, liver, muscle and brain are …
recognized. As the NAD+ concentration in human skin, blood, liver, muscle and brain are …
MetaboliteCOVID: A manually curated database of metabolite markers for COVID-19
L Ren, L Ning, Y Yang, T Yang, X Li, S Tan, P Ge… - Computers in Biology …, 2023 - Elsevier
In the realm of unraveling COVID-19's intricacies, numerous metabolomic investigations
have been conducted to discern the unique metabolic traits exhibited within infected …
have been conducted to discern the unique metabolic traits exhibited within infected …