Redox-regulated processes are relevant to wound healing. A balance between bioavailable
nitric oxide (NO) concentration and a level of oxidative and nitroxidative stress in wounds …

Phosphodiesterase type 5 (PDE5) is pivotal in cellular signalling, regulating cyclic
guanosine monophosphate (cGMP) levels crucial for smooth muscle relaxation and …

Sildenafil citrate (SC), a drug for erectile dysfunction, is now emerging as a cardiopulmonary
drug. Our study aimed to determine a novel role of sildenafil on cardioprotection through …

Abstract cGMP‐degrading pathways have received little attention in the context of
angiogenesis. In the present study we set out to determine whether cGMP‐specific …

The aim of this study was to elaborate a histological model of incisional skin wound healing
in Sprague-Dawley rats. Under aseptic conditions two paravertebral full thickness skin …

Sildenafil is the first phosphodiesterase-5 inhibitor used for the treatment of erectile
dysfunction. However, recent studies have been suggesting an antitumor effect of sildenafil …

Abstract Introduction Sildenafil Citrate has various effects on the body, including widening
blood vessels, inhibiting platelet aggregation, promoting the growth of blood vessels …

OBJECTIVE To develop a topical sildenafil hydrogel and evaluate its effect on wound
healing in dogs. ANIMALS 6 purpose-bred, sexually intact, adult Beagles. PROCEDURES …

Purpose We aimed to investigate the effect of sildenafil on the healing process of abdominal
wall wound in rats. Materials and methods The study was performed with adult female Wistar …

Effect of sildenafil citrate on the liver structure and function in obstructive jaundice: An
experimental study - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …