Current advances in skin tissue engineering and wound healing augur well for the
development of split or full thickness skin substitutes to recapitulating the native functional …

Cutaneous wound healing is a complex process, while modulating the wound
microenvironment has become an essential therapeutic goal. In clinics, advanced dressings …

Diabetic wound treatment faces significant challenges in clinical settings. Alternative
treatment approaches are needed. Continuous bleeding, disordered inflammatory …

Cardiovascular disease is the leading cause of mortality and morbidity around the globe,
creating a substantial socio-economic burden as a result. Myocardial infarction is a …

Skin and intestinal epithelial barriers play a pivotal role in protecting underlying tissues from
harsh external environments. The protective role of these epithelia is, in part, dependent on …

Hypertrophic scarring (HTS) is an aberrant form of wound healing that is associated with
excessive deposition of extracellular matrix and connective tissue at the site of injury. In this …

Hydrogel dressings not only have basic functions such as swelling, water retention, gas
permeability, and good biocompatibility but also can be endowed with advanced functions …

The foreign body reaction (FBR) is described as a local chronic inflammation after
implantation of biomaterials in which macrophages involved intimately. At the stage of acute …

Macrophages are essential immune cells and play a major role in the immune response as
pro-inflammatory or anti-inflammatory agents depending on their plasticity and functions …

Osteoarthritis (OA) is the most common form of arthritic disease, leading to disability and
impaired quality of life and no curative treatments exist. Increasing evidence indicates that …