Electrochemical HPLC Determination of Piperazine Antihistamine Drugs Employing a Spark-Generated Nickel Oxide Nanoparticle-Modified Carbon Fiber …

Z Belbasi, J Petr, J Sevcik, D Jirovsky, J Hrbac - ACS omega, 2024 - ACS Publications
In this work, we demonstrate a sensitive high-performance liquid chromatography (HPLC)
method for the determination of piperazine antihistamine drugs employing innovative …

Spectrofluorimetric approach for quantification of cyclizine in the presence of its toxic impurities in human plasma; in silico study and ADMET calculations

MY Fares, NS Abdelwahab, GM El-Sayed… - Journal of …, 2022 - Springer
Cyclizine (CYZ); an antiemetic compound; is widely misused for its euphoric or hallucinatory
effects, either by oral or intravenous routes. The concomitant abuse of CYZ among addicted …

Comparative chemometric manipulations of UV-spectrophotometric data for the efficient resolution and determination of overlapping signals of cyclizine and its …

MY Fares, NS Abdelwahab, MA Hegazy… - Journal of AOAC …, 2023 - academic.oup.com
Background Cyclizine (CYZ), a commonly used antiemetic drug, has two pharmacopeial
toxic impurities, 1-methylpiperazine (MPZ) and diphenylmethanol (DPM). When CYZ …

Determination of four pyridine alkaloids from Tripterygium wilfordii Hook. f. in human plasma by high-performance liquid chromatography coupled with mass …

M Cai, X Chen, S He, X OuYang, M Jin - Journal of Chromatography B, 2011 - Elsevier
A novel liquid chromatography–atmospheric-pressure chemical ionization–mass
spectrometry (LC–APCI/MS) method was developed and validated for the simultaneous …

[HTML][HTML] Extractive spectrophotometric assay of cyclizine in a pharmaceutical formulation and biological fluids

NH Al-Shaalan - Saudi Pharmaceutical Journal, 2012 - Elsevier
Two highly sensitive and simple spectrophotometric methods were developed to quantitate
the drug cyclizine (CYC) in its pure form and in a pharmaceutical formulation. The two …

[HTML][HTML] The pharmacokinetics and pharmacogenetics of the antiemetic cyclizine in palliative care patients

JWA Vella-Brincat, EJ Begg, BP Jensen… - Journal of pain and …, 2012 - Elsevier
CONTEXT: Cyclizine, an antihistaminic antiemetic, is commonly used in palliative care. Its
pharmacokinetics have been poorly studied, and its metabolic pathway is unknown but may …

Ecofriendly validated chromatographic methods for quantitation of cyclizine and its toxic impurities in its parenteral formulation

MM Abdelrahman, MY Fares, NS Abdelwahab… - Chromatographia, 2021 - Springer
Cyclizine (CYZ) abuse is commonly reported, either through oral or intravenous routes, for
its euphoric or hallucinatory effects. The concomitant misuse of CYZ among addicted …

Bioequivalence study of cyclizine hydrochloride 50 Mg tablets in healthy volunteers: a randomized, open-label, single-dose study

D Abhyankar, A Shedage, M Gole, P Raut - Therapeutic Delivery, 2016 - Taylor & Francis
Background: Cyclizine is used in the treatment and prevention of nausea and vomiting. We
aimed to demonstrate bioequivalence between two formulations of cyclizine 50 mg tablets …

[PDF][PDF] AVALIAÇÃO DO PAPEL DA INTERLEUCINA 4 NO PROCESSO DE OSTEOCLASTOGÊNESE MEDIADA POR RANKL

BP de Assis - cev.org.br
A hipertensão e a obesidade consistem em duas doenças de origem multifatorial que
apesar de apresentarem patogêneses distintas, apresentam uma íntima relação no seu …

Análises metagenômicas e proteômicas dos efeitos do treinamento aeróbio em modelos animais: uma visão molecular integrada da obesidade e hipertensão arterial

BP Assis - 2013 - bdtd.ucb.br
A hipertensão e a obesidade consistem em duas doenças de origem multifatorial que
apesar de apresentarem patogêneses distintas, apresentam uma íntima relação no seu …