Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …

The intestinal epithelium can be easily disrupted during gut inflammation as seen in
inflammatory bowel disease (IBD), such as ulcerative colitis or Crohn's disease. For a long …

Colorectal cancer (CRC) has one of the highest mortality rates despite the advancement of
treatment options. Aggressive CRC remains difficult to treat owing to the activation of …

Alveolar type 2 progenitor cells (AT2) seem closest to clinical translation, specifying the
evidence that AT2 may satisfactorily control the immune response to decrease lung injury by …

Abstract Purpose of Review The mechanisms involved in the TNF-mediated deregulated
bone remodeling are little appreciated. This review will discuss and summarize the impact of …

Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …

Notch signaling, a highly conserved pathway in mammals, is crucial for differentiation and
homeostasis of immune cells. Besides, this pathway is also directly involved in the …

Myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) play
critical roles in tumorigenesis. However, the mechanisms underlying MDSC and TAM …

Abstract Ethnopharmacological relevance The genus Glycyrrhiza is a small perennial herb
that has been traditionally used to treat many diseases across the world. Licorice (Gancao in …

Particulate matter (PM) increases levels of pro-inflammatory cytokines, but its effects on the
skin remain largely unknown. We investigated the signal transduction pathway and …