Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies

DP Finn, S Haroutounian, AG Hohmann, E Krane… - Pain, 2021 - journals.lww.com
This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …

Systematic review and meta-analysis of cannabinoids, cannabis-based medicines, and endocannabinoid system modulators tested for antinociceptive effects in …

N Soliman, S Haroutounian, AG Hohmann, E Krane… - Pain, 2021 - journals.lww.com
We report a systematic review and meta-analysis of studies that assessed the
antinociceptive efficacy of cannabinoids, cannabis-based medicines, and endocannabinoid …

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications

DF Levey, M Galimberti, JD Deak, FR Wendt… - Nature Genetics, 2023 - nature.com
As recreational use of cannabis is being decriminalized in many places and medical use
widely sanctioned, there are growing concerns about increases in cannabis use disorder …

Cannabidiol treatment in hand osteoarthritis and psoriatic arthritis: a randomized, double-blind, placebo-controlled trial

J Vela, L Dreyer, KK Petersen, L Arendt-Nielsen… - Pain, 2022 - journals.lww.com
Cannabidiol (CBD) is increasingly used as analgesic medication although the recent
International Association for the Study of Pain Presidential Task Force on cannabis and …

Cancer pain management: a narrative review of current concepts, strategies, and techniques

F Mestdagh, A Steyaert, P Lavand'homme - Current Oncology, 2023 - mdpi.com
Pain is frequently reported during cancer disease, and it still remains poorly controlled in
40% of patients. Recent developments in oncology have helped to better control pain …

Cannabis-based medicines and medical cannabis for chronic neuropathic pain

F Petzke, T Tölle, MA Fitzcharles, W Häuser - CNS drugs, 2022 - Springer
Neuropathic pain represents a broad category of pain syndromes that include a wide variety
of peripheral and central disorders. The overall prevalence of neuropathic pain in the …

Differential regulation of Cav3.2 and Cav2.2 calcium channels by CB1 receptors and cannabidiol

EK Harding, IA Souza, MA Gandini… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Cannabinoids are a promising therapeutic avenue for chronic
pain. However, clinical trials often fail to report analgesic efficacy of cannabinoids. Inhibition …

The endocannabinoid system and physical exercise

D Matei, D Trofin, DA Iordan, I Onu… - International journal of …, 2023 - mdpi.com
The endocannabinoid system (ECS) is involved in various processes, including brain
plasticity, learning and memory, neuronal development, nociception, inflammation, appetite …

Impacts of medical and non-medical cannabis on the health of older adults: findings from a scoping review of the literature

D Wolfe, K Corace, C Butler, D Rice, B Skidmore… - PLoS …, 2023 - journals.plos.org
Background Cannabis legalization has enabled increased consumption in older adults. Age-
related mental, physical, and physiological changes may lead to differences in effects of …

Long‐term observational studies with cannabis‐based medicines for chronic non‐cancer pain: A systematic review and meta‐analysis of effectiveness and safety

P Bialas, MA Fitzcharles, P Klose… - European Journal of …, 2022 - Wiley Online Library
Abstract Background and Objective This systematic review evaluated the effectiveness,
tolerability and safety of cannabis‐based medicines (CbMs) for chronic non‐cancer pain …