The red flour beetle T. castaneum: elaborate genetic toolkit and unbiased large scale RNAi screening to study insect biology and evolution
M Klingler, G Bucher - EvoDevo, 2022 - Springer
The red flour beetle Tribolium castaneum has emerged as an important insect model system
for a variety of topics. With respect to studying gene function, it is second only to the vinegar …
for a variety of topics. With respect to studying gene function, it is second only to the vinegar …
Butterfly eyespots evolved via cooption of an ancestral gene-regulatory network that also patterns antennae, legs, and wings
SN Murugesan, H Connahs… - Proceedings of the …, 2022 - National Acad Sciences
Butterfly eyespots are beautiful novel traits with an unknown developmental origin. Here we
show that eyespots likely originated via cooption of parts of an ancestral appendage gene …
show that eyespots likely originated via cooption of parts of an ancestral appendage gene …
iEnhancer-5Step: identifying enhancers using hidden information of DNA sequences via Chou's 5-step rule and word embedding
An enhancer is a short (50–1500bp) region of DNA that plays an important role in gene
expression and the production of RNA and proteins. Genetic variation in enhancers has …
expression and the production of RNA and proteins. Genetic variation in enhancers has …
Enhanced genome assembly and a new official gene set for Tribolium castaneum
N Herndon, J Shelton, L Gerischer, P Ioannidis… - BMC genomics, 2020 - Springer
Background The red flour beetle Tribolium castaneum has emerged as an important model
organism for the study of gene function in development and physiology, for ecological and …
organism for the study of gene function in development and physiology, for ecological and …
Patterning with clocks and genetic cascades: Segmentation and regionalization of vertebrate versus insect body plans
M Diaz-Cuadros, O Pourquié, E El-Sherif - PLoS Genetics, 2021 - journals.plos.org
Oscillatory and sequential processes have been implicated in the spatial patterning of many
embryonic tissues. For example, molecular clocks delimit segmental boundaries in …
embryonic tissues. For example, molecular clocks delimit segmental boundaries in …
iEnhancer-ECNN: identifying enhancers and their strength using ensembles of convolutional neural networks
Background Enhancers are non-coding DNA fragments which are crucial in gene regulation
(eg transcription and translation). Having high locational variation and free scattering in 98 …
(eg transcription and translation). Having high locational variation and free scattering in 98 …
Evolution and molecular mechanisms of wing plasticity in aphids
KD Deem, LE Gregory, X Liu, OS Ziabari… - Current Opinion in Insect …, 2024 - Elsevier
Highlights•Aphids produce winged and wingless phenotypes from the same
genotype.•Ecdysone and insulin signaling are important regulators of this wing …
genotype.•Ecdysone and insulin signaling are important regulators of this wing …
Conserved and novel enhancers in the Aedes aegypti single-minded locus recapitulate embryonic ventral midline gene expression
I Schember, W Reid, G Sterling-Lentsch… - PLoS …, 2024 - journals.plos.org
Transcriptional cis-regulatory modules, eg, enhancers, control the time and location of
metazoan gene expression. While changes in enhancers can provide a powerful force for …
metazoan gene expression. While changes in enhancers can provide a powerful force for …
How enhancers regulate wavelike gene expression patterns
A key problem in development is to understand how genes turn on or off at the right place
and right time during embryogenesis. Such decisions are made by non-coding sequences …
and right time during embryogenesis. Such decisions are made by non-coding sequences …