Luteolin: A promising multifunctional natural flavonoid for human diseases

M Zhu, Y Sun, Y Su, W Guan, Y Wang… - Phytotherapy …, 2024 - Wiley Online Library
Natural products are closely associated with human health. Luteolin (LUT), a flavonoid
polyphenolic compound, is widely found in fruits, vegetables, flowers, and herbs. It is …

(B, N)-codoped carbon dots for sensitive luteolin detection and HepG2 cell imaging

Y Wang, X Hou, Y Li, X Sun, R Hu, Y Lv, R Jia… - Microchemical …, 2024 - Elsevier
Abstract Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone, LTL) is a kind of hydrophobic flavonoid,
which has a number of pharmacological actions. It has a number of pharmacological …

Flavones Suppress Aggregation and Amyloid Fibril Formation of Human Lysozyme under Macromolecular Crowding Conditions

Shabnam, R Bhat - Biochemistry, 2024 - ACS Publications
The crowded milieu of a biological cell significantly impacts protein aggregation and
interactions. Understanding the effects of macromolecular crowding on the aggregation and …

Inhibition and disaggregation effect of flavonoid-derived carbonized polymer dots on protein amyloid aggregation

D Li, S Wang, J Dong, J Li, X Wang, F Liu… - Colloids and Surfaces B …, 2024 - Elsevier
In this research, four water-insoluble flavonoid compounds were utilized and reacted with
arginine to prepare four carbonized polymer dots with good water-solubility in a …

Multifunctional Carbon Dots Inhibit the Amyloid Fibrillation and Scavenge Free Radicals

D Li, X Wang, S Wang, X Song, L Fang, Y Zhang… - Journal of Molecular …, 2024 - Elsevier
In the present study, a series of seven carbon dots, either containing or lacking the N
element, were successfully synthesized via the one-pot hydrothermal method using green …

Multifunctional carbonized polymer dots: Synthesis and applications in retarding protein amyloid aggregation, capturing free radicals and cell imaging

J Li, S Wang, J Dong, D Li, X Wang, G Ma… - Journal of Molecular …, 2025 - Elsevier
In this study, a series of carbonized polymer dots were synthesized using Congo red and
tryptophan as carbon source by changing their molar ratio through simple one-step method …

[HTML][HTML] Experimental and computational investigation of the effect of Hsc70 structural variants on inhibiting amylin aggregation

A Chaari, N Saikia, P Paul, M Yousef, F Ding… - Biophysical …, 2024 - Elsevier
The misfolding and aggregation of human islet amyloid polypeptide (hIAPP), also known as
amylin, have been implicated in the pathogenesis of type 2 diabetes (T2D). Heat shock …

[引用][C] 人源溶菌酶结构与功能的研究进展

刘汝薇, 孟庆勇, 戴蕴平, 张雅丽 - 生物工程学报, 2023