Genetic compensation: A phenomenon in search of mechanisms

MA El-Brolosy, DYR Stainier - PLoS genetics, 2017 - journals.plos.org
Several recent studies in a number of model systems including zebrafish, Arabidopsis, and
mouse have revealed phenotypic differences between knockouts (ie, mutants) and …

Actin visualization at a glance

M Melak, M Plessner, R Grosse - Journal of cell science, 2017 - journals.biologists.com
Actin functions in a multitude of cellular processes owing to its ability to polymerize into
filaments, which can be further organized into higher-order structures by an array of actin …

Type-2 pericytes participate in normal and tumoral angiogenesis

A Birbrair, T Zhang, ZM Wang… - … of Physiology-Cell …, 2014 - journals.physiology.org
Tissue growth and function depend on vascularization, and vascular insufficiency or excess
exacerbates many human diseases. Identification of the biological processes involved in …

NAA80 is actin's N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility

A Drazic, H Aksnes, M Marie… - Proceedings of the …, 2018 - National Acad Sciences
Actin, one of the most abundant proteins in nature, participates in countless cellular
functions ranging from organelle trafficking and pathogen motility to cell migration and …

Visualization of dynamics of single endogenous mRNA labeled in live mouse

HY Park, H Lim, YJ Yoon, A Follenzi, C Nwokafor… - Science, 2014 - science.org
The transcription and transport of messenger RNA (mRNA) are critical steps in regulating
the spatial and temporal components of gene expression, but it has not been possible to …

[HTML][HTML] The remodelling of actin composition as a hallmark of cancer

R Suresh, RJ Diaz - Translational Oncology, 2021 - Elsevier
Actin is a key structural protein that makes up the cytoskeleton of cells, and plays a role in
functions such as division, migration, and vesicle trafficking. It comprises six different cell …

Structural insights into actin isoforms

AS Arora, HL Huang, R Singh, Y Narui, A Suchenko… - Elife, 2023 - elifesciences.org
Actin isoforms organize into distinct networks that are essential for the normal function of
eukaryotic cells. Despite a high level of sequence and structure conservation, subtle …

ACTB in cancer

C Guo, S Liu, J Wang, MZ Sun, FT Greenaway - Clinica chimica acta, 2013 - Elsevier
Beta-actin (ACTB) has traditionally been regarded as an endogenous housekeeping gene
and has been widely used as a reference gene/protein in quantifying expression levels in …

A pan-cancer analysis of the prognostic and immunological role of β-actin (ACTB) in human cancers

Y Gu, S Tang, Z Wang, L Cai, H Lian, Y Shen… - …, 2021 - Taylor & Francis
ABSTRACT Beta-actin (ACTB), a highly conserved cytoskeleton structural protein, has been
regarded as a common housekeep gene and used as a reference gene for years. However …

Genetics and mechanisms leading to human cortical malformations

DM Romero, N Bahi-Buisson, F Francis - Seminars in cell & developmental …, 2018 - Elsevier
Cerebral cortical development involves a complex series of highly regulated steps to
generate the laminated structure of the adult neocortex. Neuronal migration is a key part of …