Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

Emerging data indicate that neurological complications occur as a consequence of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The blood–brain barrier …

Ischemia-reperfusion injury is a common feature of ischemic stroke, which occurs when
blood supply is restored after a period of ischemia. Reperfusion can be achieved either by …

Over the past two decades, research has heavily emphasized basic mechanisms that
irreversibly damage brain cells after stroke. Much attention has focused on what makes …

Pneumococcal meningitis continues to be associated with high rates of mortality and long-
term neurological sequelae. The most common route of infection starts by nasopharyngeal …

1. The blood–brain barrier is essential for the maintenance and regulation of the neural
microenvironment. The main characteristic features of blood–brain barrier endothelial cells …

Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …

Brain infarction causes tissue death by ischemia due to occlusion of the cerebral vessels
and recent work has shown that post stroke inflammation contributes significantly to the …

Pathophysiology of the neurovascular unit (NVU) is commonly seen in neurological
diseases. The typical features of NVU pathophysiology include tissue hypoxia, inflammatory …