Heavy metals and human health: mechanistic insight into toxicity and counter defense system of antioxidants
Heavy metals, which have widespread environmental distribution and originate from natural
and anthropogenic sources, are common environmental pollutants. In recent decades, their …
and anthropogenic sources, are common environmental pollutants. In recent decades, their …
Melatonin: a well‐documented antioxidant with conditional pro‐oxidant actions
HM Zhang, Y Zhang - Journal of pineal research, 2014 - Wiley Online Library
Abstract Melatonin (N‐acetyl‐5‐methoxytryptamine), an indoleamine produced in many
organs including the pineal gland, was initially characterized as a hormone primarily …
organs including the pineal gland, was initially characterized as a hormone primarily …
[Retracted] Biomedical Implications of Heavy Metals Induced Imbalances in Redox Systems
B Sharma, S Singh, NJ Siddiqi - BioMed research international, 2014 - Wiley Online Library
Several workers have extensively worked out the metal induced toxicity and have reported
the toxic and carcinogenic effects of metals in human and animals. It is well known that these …
the toxic and carcinogenic effects of metals in human and animals. It is well known that these …
New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
A Fardet - Nutrition research reviews, 2010 - cambridge.org
Epidemiological studies have clearly shown that whole-grain cereals can protect against
obesity, diabetes, CVD and cancers. The specific effects of food structure (increased satiety …
obesity, diabetes, CVD and cancers. The specific effects of food structure (increased satiety …
Heavy metal induced oxidative stress & its possible reversal by chelation therapy
Exposure to heavy metals is a common phenomenon due to their environmental
pervasiveness. Metal intoxication particularly neurotoxicity, genotoxicity, or carcinogenicity is …
pervasiveness. Metal intoxication particularly neurotoxicity, genotoxicity, or carcinogenicity is …
Regulation of antioxidant enzymes: a significant role for melatonin
Antioxidant enzymes form the first line of defense against free radicals in organisms. Their
regulation depends mainly on the oxidant status of the cell, given that oxidants are their …
regulation depends mainly on the oxidant status of the cell, given that oxidants are their …
Reactive oxygen species in the regulation of synaptic plasticity and memory
CA Massaad, E Klann - Antioxidants & redox signaling, 2011 - liebertpub.com
The brain is a metabolically active organ exhibiting high oxygen consumption and robust
production of reactive oxygen species (ROS). The large amounts of ROS are kept in check …
production of reactive oxygen species (ROS). The large amounts of ROS are kept in check …
Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger
Melatonin was found to be a potent free radical scavenger in 1993. Since then over 800
publications have directly or indirectly confirmed this observation. Melatonin scavenges a …
publications have directly or indirectly confirmed this observation. Melatonin scavenges a …
Melatonin reshapes the mitochondrial network and promotes intercellular mitochondrial transfer via tunneling nanotubes after ischemic‐like injury in hippocampal …
Mitochondrial dysfunction is considered one of the hallmarks of ischemia/reperfusion injury.
Mitochondria are plastic organelles that undergo continuous biogenesis, fusion, and fission …
Mitochondria are plastic organelles that undergo continuous biogenesis, fusion, and fission …
[PDF][PDF] Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans.
This brief resume enumerates the multiple actions of melatonin as an antioxidant. This
indoleamine is produced in the vertebrate pineal gland, the retina and possibly some other …
indoleamine is produced in the vertebrate pineal gland, the retina and possibly some other …