[HTML][HTML] Overcoming cancer therapeutic bottleneck by drug repurposing
Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …
the development of the alternative strategy of drug repurposing, the development of old …
[HTML][HTML] Small molecules in the treatment of COVID-19
S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …
societies and economies. Until now, effective therapeutics against COVID-19 are in high …
From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy
T Efferth - Seminars in cancer biology, 2017 - Elsevier
Artemisia annua L. is used throughout Asia and Africa as tea and press juice to treat malaria
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …
The immunosuppressive activity of artemisinin‐type drugs towards inflammatory and autoimmune diseases
T Efferth, F Oesch - Medicinal research reviews, 2021 - Wiley Online Library
The sesquiterpene lactone artemisinin from Artemisia annua L. is well established for
malaria therapy, but its bioactivity spectrum is much broader. In this review, we give a …
malaria therapy, but its bioactivity spectrum is much broader. In this review, we give a …
Anti-SARS-CoV-2 potential of artemisinins in vitro
R Cao, H Hu, Y Li, X Wang, M Xu, J Liu… - ACS Infectious …, 2020 - ACS Publications
The discovery of novel drug candidates with anti-severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) potential is critical for the control of the global COVID-19 …
coronavirus 2 (SARS-CoV-2) potential is critical for the control of the global COVID-19 …
[HTML][HTML] The use of antimalarial drugs against viral infection
S D'Alessandro, D Scaccabarozzi, L Signorini… - Microorganisms, 2020 - mdpi.com
In recent decades, drugs used to treat malaria infection have been shown to be beneficial for
many other diseases, including viral infections. In particular, they have received special …
many other diseases, including viral infections. In particular, they have received special …
Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the
herb Artemisia annua. It has been used for centuries for the treatment of fever and chills, and …
herb Artemisia annua. It has been used for centuries for the treatment of fever and chills, and …
Plant-microbial interaction: The mechanism and the application of microbial elicitor induced secondary metabolites biosynthesis in medicinal plants
Plants and microbes interact with each other via different chemical signaling pathways. At
the risophere level, the microbes can secrete molecules, called elicitors, which act on their …
the risophere level, the microbes can secrete molecules, called elicitors, which act on their …
Artemisinins: pharmacological actions beyond anti-malarial
Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …
Therapeutic potential of medicinal plants against COVID-19: The role of antiviral medicinal metabolites
There are numerous trials underway to find treatment for the COVID-19 through testing
vaccines as well as existing drugs. Apart from the many synthetic chemical compounds …
vaccines as well as existing drugs. Apart from the many synthetic chemical compounds …