Substance use disorders (SUD) present a worldwide challenge with few effective therapies
except for the relative efficacy of opioid pharmacotherapies, despite limited treatment …

In 2020, fentanyl and its analogs contributed to~ 65% of drug-attributed fatalities in the USA,
with a threatening increasing trend during the last ten years. These synthetic opioids used …

Opioid use disorders (OUD) and opioid-related fatal overdoses are a public health concern
in the United States. Approximately 100,000 fatal opioid-related overdoses occurred …

Currently approved pharmacotherapies for opioid use disorders (OUDs) and overdose
reversal agents are insufficient to slow the spread of OUDs due to the proliferation of …

Innovative therapies to complement current treatments are needed to curb the growing
incidence of fatal overdoses related to synthetic opioids. Murine and chimeric monoclonal …

Carbon quantum dots (CQDs) have received increasing attention in recent years for their
potential toxicity. However, little is known about their neurobehavioral toxicity. This study …

Drug-related fatal overdoses have significantly increased in the past decade due to the
widespread availability of illicit fentanyl and other potent synthetic opioids such as …

Introduction Development and implementation of effective treatments for opioid use disorder
(OUD) and prevention of overdose are urgent public health needs. Though existing …

The opioid overdose epidemic is a growing and evolving public health crisis fueled by the
widespread presence of fentanyl and fentanyl analogues (F/FAs) in both street mixtures and …

Opioid use disorders (OUD) and overdoses are ever-evolving public health threats that
continue to grow in incidence and prevalence in the United States and abroad. Current …