The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable
source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by …

Multicomponent reactions (MCRs) involving a minimum of three reactants or reaction
centers are conducted in one pot and with a single operational step. This synthetic method …

A unique class of antibacterial azolylpyrimidinediols (APDs) and their analogues were
developed. Some synthesized compounds showed excellent bacteriostatic potency; …

Cancer is a leading cause of death and a major health problem worldwide. While many
effective anticancer agents are available, the majority of drugs currently on the market are …

The health crisis caused by severe multidrug resistance increasingly compels the
exploitation of new alternative antibacterial drugs. A library of structurally unique …

One of the largest classes of organic molecules are dihydropyrimidines and its derivatives.
They are widely used in a variety of pharmacological and industrial applications. Their …

In this study, two novel chemosensors containing dihydropyridine fragment namely;(2 E, 2 E
ʹ)-1, 1ʹ-(2, 6-dimethyl-1, 4-dihydropyridine-3, 5-diyl) bis (3-(4-(dimethylamino) phenyl) prop …

Biginelli-type multicomponent reactions (MCRs) with N H-free sulfonimidamides provide 2, 3-
dihydro-1, 2, 6-thiadiazine 1-oxides in high yields. The couplings are performed in a …

Nanostructured metal oxides, produced from the thermal breakdown of two new Schiff base
metal complexes of Zn (II) and Cu (II) acting as inexpensive precursors, have been …

Multicomponent reactions are considered to be of increasing importance as time progresses
due to the economic and environmental advantages such strategies entail. The three …