The psychoactive constituent in cannabis, Δ9-tetrahydrocannabinol (THC), was isolated in
the mid-1960s, but the cannabinoid receptors, CB1 and CB2, and the major endogenous …

Like human children, most young mammals devote a significant amount of time and energy
playing together, and social play is fun. Although social play is very pleasurable, it is more …

There is evidence from studies in humans and animals that a vulnerable period for chronic
cannabinoid administration exists during certain phases of development. The present study …

Cognitive deficits in schizophrenia are among the core symptoms of the disease, correlate
with functional outcome, and are not well treated with current antipsychotic therapies. In …

Cannabis has long been known to produce cognitive and emotional effects. Research has
shown that cannabinoid drugs produce these effects by driving the brain's endogenous …

Cannabis contains over 70 unique compounds and its abuse is linked to an increased risk of
developing schizophrenia. The behavioural profiles of the psychotropic cannabis constituent …

Marijuana and its psychoactive constituents induce a multitude of effects on brain function.
These include deficits in memory formation, but care needs to be exercised since many …

Currently, there is a lot of interest in cannabis use as a risk factor for the development of
schizophrenia. Cognitive dysfunction associated with long-term or heavy cannabis use is …

Although cannabis belongs to the most widely used drugs among adolescents, little is
known about its acute and lasting neurobehavioral effects during critical developmental …

Pannexin 1 (Panx1) represents a class of vertebrate membrane channels, bearing
significant sequence homology with the invertebrate gap junction proteins, the innexins and …