DNA methylation plays an important role in the maintenance of genomic stability. Ten-
eleven translocation proteins (TETs) are a family of iron (Fe2+) and α-KG-dependent …

Peripheral T cell lymphomas (PTCLs) are a heterogeneous group of orphan neoplasms.
Despite the introduction of anthracycline-based chemotherapy protocols, with or without …

In mammals, DNA methyltransferases transfer a methyl group from S-adenosylmethionine to
the 5 position of cytosine in DNA. The product of this reaction, 5-methylcytosine (5mC), has …

Abstract Aberrant changes in 5-hydroxymethylcytosine (5hmC) are a unique epigenetic
feature in many cancers including acute myeloid leukemia (AML). However, genome-wide …

Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder (PCSMLPD) is a
recently recognized entity in the 2017 World Health Organization (WHO) classification. It …

This review deals with the functional characteristics and biological roles of enzymes
participating in DNA methylation and demethylation as key factors in epigenetic regulation of …

Simple Summary This work reviews the multiple efforts that have been and are being
invested by researchers as well as clinicians to improve the treatment of a specific T-cell …

Ten eleven translocation (TET) dioxygenases 1–3 are non-heme Fe (II) and α-ketoglutarate
dependent enzymes that catalyze oxidation of 5-methylcytosine (5mC) in DNA to …

Mouse models are essential to study and comprehend normal and malignant
hematopoiesis. The ideal preclinical model should mimic closely the human malignancy …

New insights in the pathogenesis of T-cell lymphomas : Current Opinion in Oncology New
insights in the pathogenesis of T-cell lymphomas : Current Opinion in Oncology Log in or …