Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
synaptic dysfunction and accumulation of abnormal aggregates formed by amyloid‐β …

Caffeine (1, 3, 7-trimethylxanthine) is the most consumed psychoactive substance in the
world, acting by means of antagonism to adenosine receptors, mainly A1 and A2A. Coffee is …

Several lines of recent evidence indicate that the amyloid precursor protein-derived C-
terminal fragments (APP-CTFs) could correspond to an etiological trigger of Alzheimer's …

Autosomal dominant forms of familial Alzheimer's disease (FAD) are associated with
increased production of the amyloid β peptide, Aβ42, which is derived from the amyloid …

Several epidemiological studies indicate that moderate consumption of wine is associated
with a lower incidence of Alzheimer's disease. Wine is enriched in antioxidant compounds …

Tea consumption is varying its status from a mere ancient beverage and a lifestyle habit, to a
nutrient endowed with possible prospective neurobiological–pharmacological actions …

Zinc is an important trace element in biology. An important pool of zinc in the brain is the one
present in synaptic vesicles in a subgroup of glutamatergic neurons. In this form it can be …

Chronic stress and high levels of glucocorticoids produce functional and structural changes
in brain and especially in the hippocampus, an important limbic system structure that plays a …

Proproteins and prohormones are the fundamental units from which bioactive proteins and
peptides as well as neuropeptides are derived by limited proteolysis within the secretory …

The present study was designed to examine whether brain inflammation caused by systemic
administration of lipopolysaccharides (LPS) alters the expression/processing of amyloid …