New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

Surveillance studies have shown that OXA-48-like carbapenemases are the most common
carbapenemases in Enterobacterales in certain regions of the world and are being …

The ability of clinical microbiology laboratories to reliably detect carbapenemase-producing
carbapenem-resistant Enterobacteriaceae (CP-CRE) is an important element of the effort to …

The rapid spread of multidrug-resistant Gram-negative organisms constitutes one of the
greatest challenges to global health. While Gram-negative organisms have developed …

Carbapenem-resistant Enterobacteriaceae (CRE) have spread rapidly around the world in
the past few years, posing great challenges to human health. The plasmid-mediated …

Infants admitted to the neonatal intensive care unit, particularly those born preterm, are at
high risk for infection due to the combination of an immature immune system, prolonged …

Objectives The aim of this study was to evaluate the performance of five different
carbapenemase tests and to develop an algorithm which will permit the detection of most …

Increasing carbapenem resistance in Enterobacterales poses a threat to public health. In
recent decades, this increase in carbapenem resistance has been caused by the global …

Abstract Background Carbapenemase-resistant Enterobacteriaceae (CRE) cause many
serious infections resulting in increasing treatment cost, prolonged hospitalization, and …

Infections due to carbapenem-resistant Enterobacteriaceae (CRE) are increasingly
prevalent in children and are associated with poor clinical outcomes. Optimal treatment …