1. Content and composition 2. Dietary influences 3. Uptake and incorporation into complex
lipids 4. Fatty acid synthesis and its regulation 5. Fatty acid transformations (a) Fatty acid …

Many species of ganglioside GM1, differing for the sialic acid and ceramide content, have
been characterized and their physico-chemical properties have been studied in detail since …

The earliest event so far known that occurs in the brain affected with Alzheimer's disease
(AD) is the deposition and fibril formation of amyloid β–protein (Aβ). Aβ is cleaved from a …

Soluble Aβ oligomers contribute importantly to synaptotoxicity in Alzheimer's disease, but
their dynamics in vivo remain unclear. Here, we found that soluble Aβ oligomers were …

We report 2 patients with a treatable, immune‐mediated motor polyneuropathy associated
with antibodies to defined neural antigens. In these patients asymmetrical weakness …

The drastic intestinal secretion of fluid and electrolytes that is characteristic of cholera is the
result of reasonably well understood cellular and biochemical actions of the toxin secreted …

Gangliosides are a family of sialic acid-containing glycosphingolipids highly enriched in the
mammalian nervous system. Although they are the major sialoglycoconjugates in the brain …

The aggregation of α-synuclein is believed to be a key step in the etiology of Parkinson's
disease. α-Synuclein is found in the cytosol and is associated with membranes in the …

Heat-labile enterotoxin (LT) from Escherichia coli is a bacterial protein toxin with an AB 5
multimer structure, in which the B pentamer has membrane binding function and the A …

Gangliosides (sialic acid-containing glycosphingolipids) are abundant in neurons of all
animal species and play important roles in many cell physiological processes, including …