Infection microenvironment-related antibacterial nanotherapeutic strategies

Z Wang, X Liu, Y Duan, Y Huang - Biomaterials, 2022 - Elsevier
The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

Recent developments of sonodynamic therapy in antibacterial application

R Wang, Q Liu, A Gao, N Tang, Q Zhang, A Zhang… - Nanoscale, 2022 - pubs.rsc.org
The rapid emergence of pathogenic bacteria poses a serious threat to global health.
Notably, traditional antibiotic therapies suffer from the risk of strengthening bacterial drug …

Bacteria-responsive nanoliposomes as smart sonotheranostics for multidrug resistant bacterial infections

X Pang, Q Xiao, Y Cheng, E Ren, L Lian, Y Zhang… - ACS …, 2019 - ACS Publications
Rapid emergence of multidrug resistant (MDR)“superbugs” poses a severe threat to global
health. Notably, undeveloped diagnosis and concomitant treatment failure remain highly …

[HTML][HTML] Emerging nanosonosensitizers augment sonodynamic-mediated antimicrobial therapies

Q Xu, W Xiu, Q Li, Y Zhang, X Li, M Ding, D Yang… - Materials Today Bio, 2023 - Elsevier
With the widespread prevalence of drug-resistant pathogens, traditional antibiotics have
limited effectiveness and do not yield the desired outcomes. Recently, alternative …

Fluorinated carbohydrates for 18 F-positron emission tomography (PET)

E Campbell, C Jordan, R Gilmour - Chemical Society Reviews, 2023 - pubs.rsc.org
Carbohydrate diversity is foundational in the molecular literacy that regulates cellular
function and communication. Consequently, delineating and leveraging this structure …

Bacteria‐Targeted Combined with Photothermal/NO Nanoparticles for the Treatment and Diagnosis of MRSA Infection In Vivo

K Lv, G Li, X Pan, L Liu, Z Chen… - Advanced …, 2023 - Wiley Online Library
Currently, undeveloped diagnosis and delayed treatment of bacteria‐infected sites in vivo
not only expand the risk of tissue infection but are also a major clinical cause of multiple …

Maltotriose-based probes for fluorescence and photoacoustic imaging of bacterial infections

A Zlitni, G Gowrishankar, I Steinberg… - Nature …, 2020 - nature.com
Currently, there are no non-invasive tools to accurately diagnose wound and surgical site
infections before they become systemic or cause significant anatomical damage …

Chemoenzymatic Syntheses of Fluorine-18-Labeled Disaccharides from [18F] FDG Yield Potent Sensors of Living Bacteria In Vivo

AM Sorlin, M López-Álvarez, SJ Rabbitt… - Journal of the …, 2023 - ACS Publications
Chemoenzymatic techniques have been applied extensively to pharmaceutical
development, most effectively when routine synthetic methods fail. The regioselective and …

Radiotracer development for bacterial imaging

F Mota, AA Ordonez, G Firth… - Journal of medicinal …, 2020 - ACS Publications
Bacterial infections remain a major threat to humanity and are a leading cause of death and
disability. Antimicrobial resistance has been declared as one of the top ten threats to human …

Research progress of contrast agents for bacterial infection imaging in vivo

Y Zhang, M Hao, L Li, Q Luo, S Deng, Y Yang… - TrAC Trends in …, 2023 - Elsevier
Accurate and sensitive detection of pathogenic bacteria are crucial for effectively treating
bacterial infection and reducing mortality caused by bacterial infection. Contrast agent …