Key points The impact of SARS‐CoV‐2 infection on autonomic and cardiovascular function
in otherwise healthy individuals is unknown. For the first time it is shown that young adults …

Cold exposure has been considered an essential risk factor for the global disease burden,
while its role in cardiovascular diseases is still underappreciated. The increase in frequency …

Abstract Background and Objective Pain is a major clinical challenge, and understanding
the pathophysiology is critical for optimal management. The autonomic nervous system …

New Findings What is the central question of this study? Sympathetically mediated
vasoconstriction is preserved during hypoxaemia in humans, but our understanding of …

Our knowledge about how low-dose (analgesic) fentanyl affects autonomic cardiovascular
regulation is primarily limited to animal experiments. Notably, it is unknown if low-dose …

Cross‐sectional data indicate that acute SARS‐CoV‐2 infection increases resting muscle
sympathetic nerve activity (MSNA) and alters hemodynamic responses to orthostasis in …

Previous work demonstrates augmented muscle sympathetic nerve activity (MSNA)
responses to the cold pressor test (CPT) in older women. Given its interindividual variability …

Key points Low dose ketamine is a leading medication used to provide analgesia in pre‐
hospital and hospital settings. Low dose ketamine is increasingly used off‐label to treat …

Our knowledge about how low-dose (analgesic) morphine affects autonomic cardiovascular
regulation is primarily limited to animal experiments. Notably, it is unknown if low-dose …

Background: We tested the hypothesis that patients with heart failure with preserved ejection
fraction (HFpEF) would have greater muscle sympathetic nerve activity (MSNA) at rest and …