[HTML][HTML] Advances in formulation and manufacturing strategies for the delivery of therapeutic proteins and peptides in orally disintegrating dosage forms

S Bashir, R Fitaihi, HE Abdelhakim - European Journal of Pharmaceutical …, 2023 - Elsevier
Therapeutic proteins and peptides (TPPs) are increasingly favoured above small drug
molecules due to their high specificity to the site of action and reduced adverse effects …

Orodispersible tablets for pediatric drug delivery: current challenges and recent advances

R Wiedey, M Kokott, J Breitkreutz - Expert Opinion on Drug …, 2021 - Taylor & Francis
Introduction Child appropriate dosage forms are indispensable in modern medicine and are
a prerequisite for successful pediatric drug therapy. For years, experts have called for a …

RETRACTED ARTICLE: Poloxamer-407-Co-Poly (2-Acrylamido-2-Methylpropane Sulfonic Acid) Cross-linked Nanogels for Solubility Enhancement of Olanzapine …

KU Khan, N Akhtar, MU Minhas - AAPS PharmSciTech, 2020 - Springer
Current study is focused to enhance the solubility of poorly soluble drug olanzapine (OLZ)
by nanogels drug delivery system, as improved solubility is one of the most important …

β-cyclodextrin modification by cross-linking polymerization as highly porous nanomatrices for olanzapine solubility improvement; synthesis, characterization and bio …

KU Khan, MU Minhas, SF Badshah, M Sohail… - Journal of Drug Delivery …, 2022 - Elsevier
Herein, we report highly porous and amorphous nanomatrices developed by cross-linking
polymerization with subsequent condensation technique for solubility, dissolution and …

The technology for improving stability of nanosuspensions in drug delivery

W Guan, Y Ma, S Ding, Y Liu, Z Song, X Liu… - Journal of Nanoparticle …, 2022 - Springer
This review was devoted to the technology and approach for improving nanosuspensions
stability in drug delivery to retrieve the state-of-the-art nanosuspensions. The main content of …

Evaluation of suitable polymeric matrix/carriers during loading of poorly water soluble drugs onto mesoporous silica: Physical stability and in vitro supersaturation

A Kapourani, K Katopodis, V Valkanioti… - Polymers, 2024 - mdpi.com
The application of mesoporous carriers in formulations of amorphous solid dispersions
(ASDs) has been suggested to enhance the stability of amorphous drugs. However …

Fast dissolving electrospun polymeric films of anti-diabetic drug repaglinide: formulation and evaluation

S Thakkar, N More, D Sharma, G Kapusetti… - Drug development …, 2019 - Taylor & Francis
Objective: Repaglinide is a well-known FDA approved drug from category of meglitinide;
used for the treatment of diabetes. However, its use is limited because of its poor water …

[Retracted] Polyvinylpyrrolidone K‐30‐Based Crosslinked Fast Swelling Nanogels: An Impeccable Approach for Drug's Solubility Improvement

MU Minhas, KU Khan, M Sarfraz… - BioMed Research …, 2022 - Wiley Online Library
Poor solubility is a global issue of copious pharmaceutical industries as large number of
drugs in development stage as well as already marketed products are poorly soluble which …

Tabletized Nanomedicine: From the Current Scenario to Developing Future Medicine

R Tiwari, M Kolli, S Chauhan, MM Yallapu - ACS nano, 2024 - ACS Publications
The limitations of conventional therapeutic treatments prevailed in the development of
nanotechnology-based medical formulations, termed nanomedicine. Nanomedicine is an …

Preparation and characterization of parthenolide nanocrystals for enhancing therapeutic effects of sorafenib against advanced hepatocellular carcinoma

P Liang, H Wu, Z Zhang, S Jiang, H Lv - International Journal of …, 2020 - Elsevier
A novel nanocrystals delivery system of parthenolide (PTL) was designed to combined
application with sorafenib (Sora) for advanced hepatocellular carcinoma (HCC) therapy …