Evolutionary pathways and trajectories in antibiotic resistance

F Baquero, JL Martinez, V F. Lanza… - Clinical Microbiology …, 2021 - Am Soc Microbiol
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

Tumour heterogeneity and the evolutionary trade-offs of cancer

J Hausser, U Alon - Nature Reviews Cancer, 2020 - nature.com
Tumours vary in gene expression programmes and genetic alterations. Understanding this
diversity and its biological meaning requires a theoretical framework, which could in turn …

Ribosome-binding antibiotics increase bacterial longevity and growth efficiency

E Wood, H Schulenburg, P Rosenstiel… - Proceedings of the …, 2023 - National Acad Sciences
Antibiotics, by definition, reduce bacterial growth rates in optimal culture conditions;
however, the real-world environments bacteria inhabit see rapid growth punctuated by …

Relationships between intrinsic population growth rate, carrying capacity and metabolism in microbial populations

DJ Marshall, HE Cameron, M Loreau - The ISME Journal, 2023 - academic.oup.com
In their simplest form, the dynamics of populations are described in terms of two parameters:
r, the intrinsic rate of increase; and K, the carrying capacity of the population. These two …

Antibacterial Silver Nanomaterial Synthesis From Mesoflavibacter zeaxanthinifaciens and Targeting Biofilm Formation

M Oves, MA Rauf, A Hussain, HA Qari… - Frontiers in …, 2019 - frontiersin.org
Considering the significance of biological and eco-friendly nanomaterials, in the present
study, we have synthesized silver nanoparticles from the exopolysaccharide of recently …

Stability of β-lactam antibiotics in bacterial growth media

R Brouwers, H Vass, A Dawson, T Squires… - PloS one, 2020 - journals.plos.org
Laboratory assays such as MIC tests assume that antibiotic molecules are stable in the
chosen growth medium—but rapid degradation has been observed for antibiotics including …

Can antibiotic resistance genes in household food waste be reduced by earthworm vermicomposting? Underpinning mechanisms and strategies

R Fang, X Liu, Z Zheng, B Lv, J Wang, Y Su… - Reviews of …, 2023 - Springer
Hundreds of million tons of food waste (FW) is annually generated from the household
sectors. Also, it is regarded as a main conduit for the spread of antibiotic resistance genes …

Galleria mellonella as a host model to study Candida glabrata virulence and antifungal efficacy

L Ames, S Duxbury, B Pawlowska, H Ho, K Haynes… - Virulence, 2017 - Taylor & Francis
Candida species are common human fungal pathogens causing a wide range of clinical
diseases, ranging from superficial infections to life-threatening systemic disease. Superficial …

Disentangling variational bias: the roles of development, mutation, and selection

H Cai, D Melo, DL Des Marais - Trends in Genetics, 2024 - cell.com
The extraordinary diversity and adaptive fit of organisms to their environment depends
fundamentally on the availability of variation. While most population genetic frameworks …

The evolution of competitive ability

J Sakarchi, RM Germain - The American Naturalist, 2023 - journals.uchicago.edu
Competition drives evolutionary change across taxa, but our understanding of how
competitive differences among species directs the evolution of interspecific interactions …