[HTML][HTML] Modern isolation and separation techniques for extracellular vesicles

T Liangsupree, E Multia, ML Riekkola - Journal of Chromatography A, 2021 - Elsevier
Extracellular vesicles (EVs) are heterogenous membrane-bound vesicles released from
various origins. EVs play a crucial role in cellular communication and mediate several …

Development of extracellular vesicle therapeutics: Challenges, considerations, and opportunities

B Claridge, J Lozano, QH Poh… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …

Metabolically engineered stem cell–derived exosomes to regulate macrophage heterogeneity in rheumatoid arthritis

DG You, GT Lim, S Kwon, W Um, BH Oh, SH Song… - Science …, 2021 - science.org
Despite the remarkable advances in therapeutics for rheumatoid arthritis (RA), a large
number of patients still lack effective countermeasures. Recently, the reprogramming of …

Extracellular vesicles from adipose tissue‐derived stem cells alleviate osteoporosis through osteoprotegerin and miR‐21‐5p

KS Lee, J Lee, HK Kim, SH Yeom… - Journal of …, 2021 - Wiley Online Library
Osteoporosis is one of the most common skeletal disorders caused by the imbalance
between bone formation and resorption, resulting in quantitative loss of bone tissue. Since …

Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities

A Nagelkerke, M Ojansivu, L van der Koog… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …

Extracellular vesicles as next generation immunotherapeutics

DW Greening, R Xu, A Ale, CE Hagemeyer… - Seminars in Cancer …, 2023 - Elsevier
Extracellular vesicles (EVs) function as a mode of intercellular communication and
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …

The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics

A Thakur, X Ke, YW Chen, P Motallebnejad… - Protein & …, 2022 - academic.oup.com
Extracellular vesicles (EVs) are tiny biological nanovesicles ranging from approximately 30–
1000 nm in diameter that are released into the extracellular matrix of most cell types and in …

Extracellular vesicles from child gut microbiota enter into bone to preserve bone mass and strength

JH Liu, CY Chen, ZZ Liu, ZW Luo, SS Rao… - Advanced …, 2021 - Wiley Online Library
Recently, the gut microbiota (GM) has been shown to be a regulator of bone homeostasis
and the mechanisms by which GM modulates bone mass are still being investigated. Here, it …

Adipose extracellular vesicles in intercellular and inter-organ crosstalk in metabolic health and diseases

Z Huang, A Xu - Frontiers in immunology, 2021 - frontiersin.org
Adipose tissue (AT) is a highly heterogeneous and dynamic organ that plays important roles
in regulating energy metabolism and insulin sensitivity. In addition to its classical roles in …

[HTML][HTML] Current understanding of the role of Adipose-derived Extracellular Vesicles in Metabolic Homeostasis and Diseases: Communication from the distance …

CJ Li, QH Fang, ML Liu, JN Lin - Theranostics, 2020 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) including exosomes, microvesicles (MVs), and apoptotic bodies,
are small membrane vesicular structures that are released during cell activation …