Critical appraisal beyond clinical guidelines for intraabdominal candidiasis
Background Regardless of the available antifungals, intraabdominal candidiasis (IAC)
mortality continues to be high and represents a challenge for clinicians. Main body This …
mortality continues to be high and represents a challenge for clinicians. Main body This …
Antifungal dosing in critically ill patients on extracorporeal membrane oxygenation
Extracorporeal membrane oxygenation (ECMO) is an established advanced life support
system, providing temporary cardiac and/or respiratory support in critically ill patients …
system, providing temporary cardiac and/or respiratory support in critically ill patients …
[HTML][HTML] The battle against fungi: lessons in antifungal stewardship from COVID 19 times
The COVID-19 pandemic has highlighted the detrimental effect of secondary pathogens in
patients with a primary viral insult. In addition to superinfections with bacterial pathogens …
patients with a primary viral insult. In addition to superinfections with bacterial pathogens …
Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis
E Novy, C Roger, JA Roberts, MO Cotta - Critical Care, 2023 - Springer
Intra-abdominal candidiasis (IAC) is one of the most common of invasive candidiasis
observed in critically ill patients. It is associated with high mortality, with up to 50% of deaths …
observed in critically ill patients. It is associated with high mortality, with up to 50% of deaths …
Clinical and demographic factors affecting trough levels of isavuconazole in critically ill patients with or without COVID‐19
Background The broad‐spectrum antifungal isavuconazole is administered to treat invasive
aspergillosis and mucormycosis. Objectives Isavuconazole plasma concentrations in …
aspergillosis and mucormycosis. Objectives Isavuconazole plasma concentrations in …
UPLC–MS/MS method for fluconazole determination in plasma and its application in Mexican patients with candidaemia
KP Valero Rivera, MM Aquino, JS Azúa… - Bioanalysis, 2024 - Taylor & Francis
Aim: An accurate and fast ultra-high performance liquid chromatography coupled with
tandem mass spectrometry analytical method was developed and validated for quantifying …
tandem mass spectrometry analytical method was developed and validated for quantifying …
Oral flucytosine dosing in peritoneal dialysis
WD Kufel, K Priyank - Antimicrobial Agents and Chemotherapy, 2024 - journals.asm.org
Cryptococcosis is an invasive fungal infection associated with considerable morbidity and
mortality (1). Initial treatment regimens typically include flucytosine, and dosing regimens are …
mortality (1). Initial treatment regimens typically include flucytosine, and dosing regimens are …
Ligand-and Structure-Based Virtual Screening Identifies New Inhibitors of the Interaction of the SARS-CoV-2 Spike Protein with the ACE2 Host Receptor
T Delgado-Maldonado, A González-González… - Pharmaceutics, 2024 - mdpi.com
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a fast-spreading
viral pathogen and poses a serious threat to human health. New SARS-CoV-2 variants have …
viral pathogen and poses a serious threat to human health. New SARS-CoV-2 variants have …
Clinical treatment of cryptococcal meningitis: an evidence-based review on the emerging clinical data
MZ Liu, XH Dai, MT Zeng, EQ Chen - Journal of Neurology, 2024 - Springer
Cryptococcal meningitis (CM) is a fatal fungal central nervous system (CNS) infection
caused by Cryptococcus infecting the meninges and/or brain parenchyma, with fever …
caused by Cryptococcus infecting the meninges and/or brain parenchyma, with fever …
Diagnosis and management of invasive fungal diseases in non-neutropenic ICU patients, with focus on candidiasis and aspergillosis: a comprehensive review
A Azim, A Ahmed - Frontiers in Cellular and Infection Microbiology, 2024 - frontiersin.org
Invasive fungal diseases pose a significant threat to non-neutropenic ICU patients, with
Candida and Aspergillus infections being the most common. However, diagnosing these …
Candida and Aspergillus infections being the most common. However, diagnosing these …