Background Obesity is a well-established risk factor in the development of colorectal cancer;
however, the mechanism mediating this relationship is not well understood. The adipokine …

Background Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide,
but if discovered at an early stage, the survival rate is high. The aim of this study was to …

Background Glycemic traits—such as hyperinsulinemia, hyperglycemia, and type 2 diabetes—
have been associated with higher colorectal cancer risk in observational studies; however …

Colorectal cancer prognosis is dependent on stage, and measures to improve early
detection are urgently needed. Using prospectively collected plasma samples from the …

Obesity and metabolic dysfunction are implicated in colorectal cancer development. Appetite-
regulating gut hormones might have a role in colorectal cancer risk. We investigated …

Cancer therapies, notably chemotherapy, have significantly improved survival rates and
quality of life for many patients. However, chemotherapy's cytotoxic effects also impact …

Leptin循环水平与结直肠腺瘤及结直肠癌的关联性：一项病例对照和孟德尔随机化研究- PMC Back
to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …

Diabetes is an established risk factor for colorectal cancer. However, colorectal cancer is a
heterogeneous disease and it is not well understood whether diabetes is more strongly …

Background: Inflammation has been implicated in colorectal cancer etiology, but the
relationship between C-reactive protein (CRP) and colorectal cancer risk is unclear. We …

Objective To explore the causal association between circulating leptin levels and the risk of
colorectal adenoma and colorectal cancer. Methods We collected demographic and clinical …