Conventional and emerging strategies for the fabrication and functionalization of PDMS-based microfluidic devices
Microfluidics is an emerging and multidisciplinary field that is of great interest to
manufacturers in medicine, biotechnology, and chemistry, as it provides unique tools for the …
manufacturers in medicine, biotechnology, and chemistry, as it provides unique tools for the …
Microfluidic organs-on-chips
An organ-on-a-chip is a microfluidic cell culture device created with microchip manufacturing
methods that contains continuously perfused chambers inhabited by living cells arranged to …
methods that contains continuously perfused chambers inhabited by living cells arranged to …
Microfabrication of human organs-on-chips
Abstract'Organs-on-chips' are microengineered biomimetic systems containing microfluidic
channels lined by living human cells, which replicate key functional units of living organs to …
channels lined by living human cells, which replicate key functional units of living organs to …
Lung-on-a-chip: the future of respiratory disease models and pharmacological studies
J Shrestha, S Razavi Bazaz… - Critical reviews in …, 2020 - Taylor & Francis
Abstract Recently, organ-on-a-chip models, which are microfluidic devices that mimic the
cellular architecture and physiological environment of an organ, have been developed and …
cellular architecture and physiological environment of an organ, have been developed and …
[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …
human physiopathology with striking discrepancies in estimating drug efficacy and side …
Recurrent urinary tract infection: a mystery in search of better model systems
BO Murray, C Flores, C Williams… - Frontiers in cellular …, 2021 - frontiersin.org
Urinary tract infections (UTIs) are among the most common infectious diseases worldwide
but are significantly understudied. Uropathogenic E. coli (UPEC) accounts for a significant …
but are significantly understudied. Uropathogenic E. coli (UPEC) accounts for a significant …
Organ‐on‐a‐Chip Systems: microengineering to biomimic living systems
“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …
biomimetic principles to create key aspects of living organs faithfully, including critical …
Microfluidics: reframing biological enquiry
The underlying physical properties of microfluidic tools have led to new biological insights
through the development of microsystems that can manipulate, mimic and measure biology …
through the development of microsystems that can manipulate, mimic and measure biology …
Microfluidic tissue engineering and bio‐actuation
Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …
Heart-on-a-chip platforms and biosensor integration for disease modeling and phenotypic drug screening
Heart disease is the leading cause of death worldwide and imposes a significant burden on
healthcare systems globally. A major hurdle to the development of more effective …
healthcare systems globally. A major hurdle to the development of more effective …