The demand for biomaterials that promote the repair, replacement, or restoration of hard and
soft tissues continues to grow as the population ages. Traditionally, smart biomaterials have …

Repairing articular osteochondral defects present considerable challenges in self‐repair
due to the complex tissue structure and low proliferation of chondrocytes. Conventional …

An appropriate cell microenvironment is key to tissue engineering and regenerative
medicine. Revealing the factors that influence the cell microenvironment is a fundamental …

Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

Bone-mimetic scaffolds are receiving much interest as such scaffolds exhibit excellent
biocompatibility and very close mimic to bone structure and composition. Here, novel bone …

Significant research and development in the field of biomedical implants has evoked the
scope to treat a broad range of orthopedic ailments that include fracture fixation, total bone …

Regenerative engineering holds the potential to treat clinically pervasive osteochondral
defects (OCDs). In a synthetic materials-guided approach, the scaffold's chemical and …

Lower back pain is mainly caused by intervertebral disc degeneration, in which calcification
is frequently involved. Here novel nanofibrous spongy microspheres (NF-SMS) are used to …

Kartogenin, a small and heterocyclic molecule, has emerged as a promising therapeutic
agent for incorporation into biomaterials, owing to its unique physicochemical and biological …

Musculoskeletal diseases are increasing the prevalence of physical disability worldwide.
Within the body, musculoskeletal soft and hard tissues integrate through specific multitissue …