[HTML][HTML] Transcriptomics data mining to uncover signature genes in head and neck squamous cell carcinoma: a bioinformatics analysis and RNA-sequencing based …

W Yu, X He, C Zhang, H Huangfu - American Journal of Cancer …, 2023 - ncbi.nlm.nih.gov
Due to its heterogeneous nature, head and neck squamous cell carcinoma (HNSC) had the
worst prognosis. Hence, there is an urgent need to develop novel diagnostic and prognostic …

[HTML][HTML] Detection of clinically important BRCA gene mutations in ovarian cancer patients using next generation sequencing analysis

Y Zhang, A Ali, J Xie - American Journal of Cancer Research, 2023 - ncbi.nlm.nih.gov
Ovarian cancer, a complex and aggressive malignancy, remains a significant challenge in
clinical oncology due to its heterogeneous nature and limited therapeutic options. In this …

[HTML][HTML] Investigating novel biomarkers in uterine corpus endometrial carcinoma: in silico analysis and clinical specimens validation via RT-qPCR and …

J Li, F Ramzan, G Zhong - American Journal of Cancer Research, 2023 - ncbi.nlm.nih.gov
The rising incidence and mortality rate of Uterine Corpus Endometrial Carcinoma (UCEC)
pose significant health concerns. CC and CXC chemokines have been linked to …

[HTML][HTML] Unveiling pathogenic mutations in BRCA1 and BRCA2 genes across head and neck squamous cell carcinoma patients via next generation sequencing

X Wei, Z Tian, F Zhao, A Sun, S Zhao… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Abstract Head and Neck Squamous Cell Carcinoma (HNSC) presents a formidable
challenge in the field of oncology due to its aggressive nature and the limited therapeutic …

[HTML][HTML] Identification of useful biomolecular markers in kidney renal clear cell carcinoma: an in silico and in vitro analysis-based study

K Sheikh, KN Memon, H Usman… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Kidney renal clear cell carcinoma (KIRC) is the most prevalent type of renal cell
carcinoma (RCC), with a high incidence and mortality rate. There is a lack of sensitive …

[HTML][HTML] Integrated multiplex network based approach reveled CC and CXC chemokines associated key biomarkers in colon adenocarcinoma patients

W Huang, Y Hu, X Zhang, Y Xu, Z Sun… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Colon adenocarcinoma (COAD) is a prevalent and aggressive form of cancer that
necessitates the identification of robust biomarkers for early diagnosis and treatment …

[HTML][HTML] Whole Exome Sequencing reveals clinically important pathogenic mutations in DNA repair genes across lung cancer patients

L Wang, Y Ma, W Han, Q Yang… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Lung cancer remains a substantial health challenge, with distinct genetic factors influencing
disease susceptibility and progression. This study aimed to decipher the landscape of DNA …

[HTML][HTML] Deciphering DNA repair gene mutational landscape in uterine corpus endometrial carcinoma patients using next generation sequencing

J Lou, X Chu, X Yang, M Jamil… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Abstract Uterine Corpus Endometrial Carcinoma (UCEC) is a significant health concern with
a complex genetic landscape impacting disease susceptibility and progression. This study …

[HTML][HTML] The discovery of promising candidate biomarkers in kidney renal clear cell carcinoma: evidence from the in-depth analysis of high-throughput data

X Li, M Li, T Zhao, J Zhang - American Journal of Cancer Research, 2023 - ncbi.nlm.nih.gov
Kidney renal clear cell carcinoma (KIRC) is the most prevalent subtype of renal tumor. The
underlying mechanisms governing KIRC initiation and progression are less known. The …

[HTML][HTML] Immune modulation and prognostic significance of MCM10 in pan-cancer: a comprehensive analysis

MA Abdel-Maksoud, K Iqbal, S Gull… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Oncogenic processes in cancer are often characterized by dysregulation of
critical genes. Our study focused on the minichromosome maintenance 10 replication …